Miles R H, Carballo R E, Prinz R A, McMahon M, Pulawski G, Olen R N, Dahlinghaus D L
Department of Surgery, Loyola University Medical Center, Maywood, IL 60153.
Surgery. 1992 Oct;112(4):818-22; discussion 822-3.
Morbid obesity has been considered a contraindication to laparoscopic cholecystectomy (LC).
To evaluate this we reviewed our first 201 patients undergoing LC and compared the operative procedure and outcome in morbidly obese (greater than or equal to 100 pounds over ideal body weight [IBW]) and nonobese patients. We also compared a group of morbidly obese patients who underwent standard open cholecystectomy (n = 11) with the obese group undergoing LC (n = 21). All groups were comparable in terms of age, sex, and symptoms (acute vs chronic). The obese groups undergoing LC and open cholecystectomy had similar weights (134.0 +/- 9.4 pounds over IBW [range, 100 to 286 pounds] and 133.8 +/- 6.0 pounds over IBW [range, 108 to 170 pounds], respectively) and were significantly different from the nonobese group undergoing LC (28.3 +/- 2.0 pounds over IBW [range, 23 to 98 pounds]). Parameters evaluated included operative time, resumption of normal diet, length of postoperative hospitalization, complications, conversion to open procedure, and ability to perform cholangiography.
There were no statistically significant differences between the obese and nonobese groups undergoing LC in any parameters studied (operative time, 151.7 +/- 4.0 minutes vs 160.7 +/- 9.9 minutes; tolerance of diet, 1.2 +/- 0.1 days vs 1.1 +/- 0.1 days; time to discharge, 2.0 +/- 0.1 days vs 1.8 +/- 0.2 days; complications, 7.0% vs 0.0%). Operative time (117.6 +/- 11.6 minutes) was shorter (p = 0.45) in obese patients undergoing open cholecystectomy. However, time to normal diet and length of postoperative hospitalization were significantly longer (3.1 and 4.6 days, respectively; p less than 0.01), and there were more complications (18.2%).
Rather than being contraindicated in the morbidly obese, LC appears to be the preferred method of cholecystectomy.
病态肥胖一直被视为腹腔镜胆囊切除术(LC)的禁忌证。
为评估这一点,我们回顾了最初接受LC的201例患者,并比较了病态肥胖(超过理想体重[IBW]100磅及以上)和非肥胖患者的手术过程及结果。我们还比较了一组接受标准开腹胆囊切除术的病态肥胖患者(n = 11)与接受LC的肥胖患者组(n = 21)。所有组在年龄、性别和症状(急性与慢性)方面具有可比性。接受LC和开腹胆囊切除术的肥胖组体重相似(分别比IBW重134.0±9.4磅[范围为100至286磅]和比IBW重133.8±6.0磅[范围为108至170磅]),与接受LC的非肥胖组(比IBW重28.3±2.0磅[范围为23至98磅])有显著差异。评估的参数包括手术时间、恢复正常饮食时间、术后住院时间、并发症、转为开腹手术以及进行胆管造影的能力。
在研究的任何参数方面,接受LC的肥胖组和非肥胖组之间均无统计学显著差异(手术时间,151.7±4.0分钟对160.7±9.9分钟;饮食耐受性,1.2±0.1天对1.1±0.1天;出院时间,2.0±0.1天对1.8±0.2天;并发症,7.0%对0.0%)。接受开腹胆囊切除术的肥胖患者手术时间(117.6±11.6分钟)较短(p = 0.45)。然而,恢复正常饮食时间和术后住院时间显著更长(分别为3.1天和4.6天;p<0.01),且并发症更多(18.2%)。
LC似乎是病态肥胖患者胆囊切除术的首选方法,而非禁忌证。