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[炎症性风湿性疾病中的AA型淀粉样变性。临床经验报告]

[AA-amyloidosis in inflammatory rheumatic diseases. A report of clinical experiences].

作者信息

Schneider F

机构信息

Rheumaklinik Oberammergau.

出版信息

Z Rheumatol. 1992 Jul-Aug;51(4):177-82.

PMID:1414042
Abstract

A review of the literature on rheumatic diseases with secondary amyloidosis and our diagnostic and therapeutic experiences in 33 own cases were reported. The place of subcutaneous fat biopsy in the diagnosis of secondary amyloidosis was shown included our own results and the corresponding literature. We saw amyloidosis type AA mostly in patients with high disease activity and progressive stage. There is no sure relationship to the duration of the disease. The renal involvement is clinical most significantly and also most frequently. The renal amyloidosis type AA can be influenced therapeutically however only in normal or unimportant restricted renal function. The therapeutic success is not depended on the choice of the long acting antirheumatic drug. The results were discussed in respect with the current literature.

摘要

本文报告了对伴有继发性淀粉样变性的风湿性疾病的文献综述以及我们对33例自身病例的诊断和治疗经验。皮下脂肪活检在继发性淀粉样变性诊断中的地位得以展现,其中包括我们自己的结果以及相应的文献。我们发现AA型淀粉样变性多见于疾病活动度高和处于进展期的患者。与疾病持续时间没有确切关系。肾脏受累在临床上最为显著,也是最常见的。然而,AA型肾淀粉样变性仅在肾功能正常或受限程度不严重时可进行治疗干预。治疗成功与否并不取决于长效抗风湿药物的选择。结合当前文献对结果进行了讨论。

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