凝血试验的初步经验。

INITIAL EXPERIENCE WITH THROMBOTEST.

作者信息

MILLER A L, FARRER-BROWN G, PETHER J

出版信息

J Clin Pathol. 1964 Mar;17(2):182-4. doi: 10.1136/jcp.17.2.182.

DOI:10.1136/jcp.17.2.182

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC480713/

Abstract

The initial experience of using Thrombotest instead of Quick's one-stage prothrombin time to control anticoagulant therapy is described.Patients well controlled by the Quick test are often found to be over-anticoagulated by Thrombotest standards, so the introduction of Thrombotest has led to widespread reductions in dosage. No improvement in stability of control has been noted. The main advantages of Thrombotest seem to be its technical simplicity and the comparability of results obtained in different laboratories.

摘要

本文描述了使用凝血检验（Thrombotest）而非奎克氏一步法凝血酶原时间来控制抗凝治疗的初步经验。常发现用奎克氏检验控制良好的患者，按照凝血检验的标准来看处于抗凝过度状态，因此凝血检验的引入导致了用药剂量的普遍减少。尚未观察到控制稳定性有所改善。凝血检验的主要优点似乎是其技术操作简单，以及在不同实验室获得的结果具有可比性。

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引用本文的文献

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Postgrad Med J. 1965 Sep;41(479):563-5. doi: 10.1136/pgmj.41.479.563.

本文引用的文献

1

Relation between levels of plasma thromboplastin component (PTC) and prothrombin times by the P&P and Quick methods in patients receiving warfarin.

N Engl J Med. 1962 Jul 19;267:125-30. doi: 10.1056/NEJM196207192670303.

2

Comparison of the thrombotest with the one-stage prothrombin time.

N Engl J Med. 1961 Dec 28;265:1286-9. doi: 10.1056/NEJM196112282652604.

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Thrombotest. A new method for controlling anticoagulant therapy.

Lancet. 1959 Nov 7;2(7106):754-8. doi: 10.1016/s0140-6736(59)90857-8.

4

Control of anticoagulant therapy. A comparison of the thrombotest, the prothrombin-proconvertin method, and the prothrombin time.

Acta Med Scand. 1962 Sep;172:363-7.

5

Thrombotest versus one-stage prothrombin-time determination.

N Engl J Med. 1961 Apr 6;264:681-4. doi: 10.1056/NEJM196104062641401.

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