Bando K, Obayashi M, Tsuneharu F
Department of Neurosurgery, Oita Nakamura Hospital, Japan.
No Shinkei Geka. 1992 Nov;20(11):1189-94.
We encountered a rare case of subfrontal schwannoma. A 55-year-old woman had received resection of a left frontal tumor because of hyposmia, at the age of 28 years. On June 10, 1989, she was admitted with the chief complaint of progressive contraction of visual field. Neurologic examination revealed anosmia, impaired vision and concentric contraction of visual field. Fundoscopy showed optic atrophy. CT examination demonstrated a calcified mass of mixed density which was occupying her nasal cavity, ethmoid sinus and anterior skull base. The lesion was enhanced with contrast medium. MRI clearly depicted the extension of the lesion and a low signal intensity area in the left frontal lobe as a postoperative scar. Angiography showed hypovascularity. The tumor was totally removed by bifrontal craniotomy on August 22, 1989. Infiltration into the brain or compression of the optic nerve was not detected. The dura on the cranial base side was damaged and lost by infiltration of the tumor, normal olfactory bulb was not able to be identified, and the cribriform plate was broken. The anterior skull base was reconstituted by covering the dural defect with cadaveric dura and the bony defect with a pericranium. HE staining showed Antoni A&B types of schwannoma. Postoperative course was uneventful. In this case, it is most likely that a remnant of the tumor resected when she was 28 years old had developed subfrontal schwannoma a long time after the operation, although the histological type at that time was unknown. It is also possible that a primary tumor in the nasal cavity or paranasal sinus may have extended into the cranium.(ABSTRACT TRUNCATED AT 250 WORDS)
我们遇到了一例罕见的额下神经鞘瘤。一名55岁女性在28岁时因嗅觉减退接受了左侧额叶肿瘤切除术。1989年6月10日,她因视野逐渐缩小为主诉入院。神经系统检查发现嗅觉丧失、视力受损和视野向心性缩小。眼底检查显示视神经萎缩。CT检查显示一个混合密度的钙化肿块,占据鼻腔、筛窦和前颅底。病变在注射造影剂后有强化。MRI清晰地显示了病变的范围以及左额叶的一个低信号强度区域为术后瘢痕。血管造影显示血供减少。1989年8月22日通过双额开颅手术将肿瘤完全切除。未发现肿瘤浸润入脑或压迫视神经。颅底侧的硬脑膜因肿瘤浸润而受损缺失,无法识别正常的嗅球,筛板破裂。用尸体硬脑膜覆盖硬脑膜缺损,用颅骨膜覆盖骨缺损对前颅底进行了重建。苏木精-伊红染色显示为Antoni A型和B型神经鞘瘤。术后过程顺利。在该病例中,很可能是她28岁时切除的肿瘤残余在术后很长时间发展为额下神经鞘瘤,尽管当时的组织学类型未知。也有可能鼻腔或鼻窦的原发性肿瘤扩展到了颅骨内。(摘要截短于250字)