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长期气管切开的儿童是否应切除肉芽肿?

Should granulomas be excised in children with long-term tracheotomy?

作者信息

Rosenfeld R M, Stool S E

机构信息

Department of Otolaryngology, Children's National Medical Center, Washington, DC.

出版信息

Arch Otolaryngol Head Neck Surg. 1992 Dec;118(12):1323-7. doi: 10.1001/archotol.1992.01880120049010.

Abstract

We reviewed 265 rigid bronchoscopies performed in 50 children with tracheotomy-dependent subglottic stenosis (25 congenital, 25 acquired). Granulomas developed in 40 children (80%) and were unrelated to age, sex, race, gastroesophageal reflux, tracheotomy duration, or type of stenosis. The incidence of small to medium, large, and obstructing granulomas at endoscopy was 28%, 6%, and 0%, respectively. Compared with a baseline finding of no granuloma at preceding bronchoscopy, the odds of granuloma recurrence were 3.0 after an unexcised granuloma (95% confidence interval [CI], 1.1 to 8.4), 4.1 after granuloma excision (95% CI, 1.4 to 11.9), and 7.3 after expansion surgery (95% CI, 1.1 to 49.2). Considering the low incidence of large or obstructing granulomas, and the failure of granuloma excision to diminish recurrence, we do not recommend interval excision of nonobstructing granulomas in children with stable tracheotomies.

摘要

我们回顾了50例依赖气管切开的声门下狭窄患儿(25例先天性,25例后天性)接受的265次硬质支气管镜检查。40例患儿(80%)出现肉芽肿,且与年龄、性别、种族、胃食管反流、气管切开持续时间或狭窄类型无关。内镜检查时小至中等大小、大的及阻塞性肉芽肿的发生率分别为28%、6%和0%。与前次支气管镜检查时无肉芽肿的基线发现相比,未切除肉芽肿后肉芽肿复发的几率为3.0(95%置信区间[CI],1.1至8.4),肉芽肿切除后为4.1(95%CI,1.4至11.9),扩张手术后为7.3(95%CI,1.1至49.2)。鉴于大的或阻塞性肉芽肿的发生率较低,且肉芽肿切除未能减少复发,我们不建议对气管切开稳定的患儿定期切除非阻塞性肉芽肿。

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