Biskri Latefa, Mazel Didier
Unité de Programmation Moléculaire et Toxicologie Génétique, CNRS URA 1444, Département de Microbiologie Fondamentale et Médicale, Institut Pasteur, 75724, Paris, France.
Antimicrob Agents Chemother. 2003 Oct;47(10):3326-31. doi: 10.1128/AAC.47.10.3326-3331.2003.
The gene ere(A) of the plasmid pIP1100 is larger than originally reported and is organized as an integron gene cassette. The ere(A) gene cassette carries its own promoter and is propagated by a class 2 integron with an insertion sequence element, IS1, inserted upstream of the intI2 gene. The mobility of the ere(A) cassette has been demonstrated.
质粒pIP1100的ere(A)基因比最初报道的要大,并且被组织成一个整合子基因盒。ere(A)基因盒携带自身的启动子,并通过一个2类整合子进行传播,该整合子带有一个插入序列元件IS1,插入在intI2基因的上游。ere(A)基因盒的可移动性已得到证实。