甲型肝炎的免疫发病机制。
Immune pathogenesis of hepatitis A.
作者信息
Vallbracht A, Fleischer B
机构信息
Abteilung Medizinische Virologie, Universität Tübingen, Federal Republic of Germany.
出版信息
Arch Virol Suppl. 1992;4:3-4. doi: 10.1007/978-3-7091-5633-9_1.
PMID:1450708
Abstract
In an effort to elucidate the mechanism of liver damage resulting from Hepatitis A virus (HAV) infection, we have studied infected skin fibroblasts and autologous lymphocytes from HAV patients. We report here that HLA-restricted virus-specific T cells play an essential role in HAV-related hepatocellular injury.
摘要
为了阐明甲型肝炎病毒（HAV）感染导致肝损伤的机制，我们研究了HAV患者受感染的皮肤成纤维细胞和自体淋巴细胞。我们在此报告，HLA限制的病毒特异性T细胞在HAV相关的肝细胞损伤中起重要作用。
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