Toyoda Takashi, Matsumoto Hideo, Tsuji Takashi, Kinouchi Junnosuke, Fujikawa Kyosuke
Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan.
J Arthroplasty. 2003 Sep;18(6):760-4. doi: 10.1016/s0883-5403(03)00194-3.
The incidence of heterotopic ossification (HO) after total knee arthroplasty (TKA) and its effect on the postoperative range of motion (ROM) were assessed in 63 primary TKAs. Twenty-five of 63 knees (39%) showed postoperative HO, most of which were found in the region anterior to the distal femur. The incidence of HO was significantly higher (P <.05) in the osteoarthritic knees than in the rheumatoid knees. Significant positive correlation was seen between the preoperative grade of osteophyte formation and the incidence of postoperative HO. The ROM in the knees with HO was not significantly different than that in the knees without HO at 1 year after surgery. Thus, we concluded that HO after TKA is a self-limiting condition and its pathogenesis is completely different from that of myositis ossificance.
在63例初次全膝关节置换术(TKA)中评估了异位骨化(HO)的发生率及其对术后活动范围(ROM)的影响。63个膝关节中有25个(39%)出现术后HO,其中大部分位于股骨远端前方区域。骨关节炎膝关节中HO的发生率显著高于类风湿性膝关节(P <.05)。术前骨赘形成程度与术后HO发生率之间存在显著正相关。术后1年,有HO的膝关节的ROM与无HO的膝关节相比无显著差异。因此,我们得出结论,TKA术后的HO是一种自限性疾病,其发病机制与骨化性肌炎完全不同。