Stiell Ian, Nichol Graham, Wells George, De Maio Valerie, Nesbitt Lisa, Blackburn Josée, Spaite Daniel
Clinical Epidemiology Unit, Office F657, Ottawa Health Research Institute, 1053 Carling Ave, Ottawa, Ontario K1Y 4E9, Canada.
Circulation. 2003 Oct 21;108(16):1939-44. doi: 10.1161/01.CIR.0000095028.95929.B0. Epub 2003 Oct 6.
This study evaluated the prehospital factors associated with better health-related quality of life for survivors of out-of-hospital cardiac arrest.
This prospective, 20-community, cohort study involved consecutive, adult out-of-hospital cardiac arrest patients who survived to 1 year. Patients were contacted by telephone and evaluated for the Health Utilities Index Mark III (HUI3), which describes health as a utility score on a scale from 0 (dead) to 1.0 (perfect health). The 8091 cardiac arrest patients had overall survival rates of 5.2% to hospital discharge and 4.0% to 1 year. We successfully contacted and evaluated 268 of 316 (84.8%) of known 1-year survivors. The median HUI3 score was 0.80 (interquartile range, 0.50 to 0.97), which compares well with age-adjusted values for the general population (0.83). Logistic regression identified 2 factors independently associated with very good quality of life (HUI3 >0.90) and their odds ratios (95% CIs), as follows: age 80 years or older, 0.3 (0.1 to 0.84), and citizen-initiated cardiopulmonary resuscitation (CPR), 2.0 (1.2 to 3.4) (Hosmer-Lemeshow goodness-of-fit statistic, 0.74).
This study is the largest ever conducted for out-of-hospital cardiac arrest survivors, clearly shows that these patients have good quality of life, and is the first to demonstrate that citizen-initiated CPR is strongly and independently associated with better quality of life. These results emphasize the importance of optimizing community citizen CPR readiness. Given the low rate of citizen-initiated CPR in many communities, we believe that local and national initiatives should vigorously promote the practice of bystander CPR.
本研究评估了院外心脏骤停幸存者健康相关生活质量较好的院前因素。
这项前瞻性、涉及20个社区的队列研究纳入了连续的成年院外心脏骤停幸存者,随访至1年。通过电话联系患者,并使用健康效用指数Mark III(HUI3)进行评估,该指数将健康描述为从0(死亡)到1.0(完美健康)的效用分数。8091例心脏骤停患者的总体生存率为:出院时5.2%,1年时4.0%。我们成功联系并评估了已知的316例1年幸存者中的268例(84.8%)。HUI3评分中位数为0.80(四分位间距,0.50至0.97),与一般人群的年龄校正值(0.83)相当。逻辑回归确定了2个与非常好的生活质量(HUI3>0.90)独立相关的因素及其比值比(95%可信区间),如下:80岁及以上年龄,0.3(0.1至0.84);公民发起的心肺复苏(CPR),2.0(1.2至3.4)(Hosmer-Lemeshow拟合优度统计量,0.74)。
本研究是针对院外心脏骤停幸存者开展的规模最大的研究,明确表明这些患者生活质量良好,并且首次证明公民发起的心肺复苏与更好的生活质量密切且独立相关。这些结果强调了优化社区公民心肺复苏准备情况的重要性。鉴于许多社区公民发起的心肺复苏率较低,我们认为地方和国家层面的举措应大力推广旁观者心肺复苏的实施。