Wu Tsu-Lan, Chia Ju-Hsin, Su Lin-Hui, Kuo An-Jing, Chu Chishih, Chiu Cheng-Hsun
Department of Clinical Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
J Clin Microbiol. 2003 Oct;41(10):4836-8. doi: 10.1128/JCM.41.10.4836-4838.2003.
To study the growing trend of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in pediatric intensive care units (PICUs), 88 nonrepetitive ESBL-producing isolates were prospectively collected and analyzed by molecular methods during a 16-month period. The emergence and dissemination of ESBL-producing Enterobacteriaceae in PICUs are the consequence of the clonal dissemination of a few epidemic strains along with the horizontal transmission of resistance gene-carrying plasmids among bacterial organisms.
为研究儿科重症监护病房(PICUs)中产超广谱β-内酰胺酶(ESBL)肠杆菌科细菌的增长趋势,在16个月期间前瞻性收集了88株非重复产ESBL分离株,并采用分子方法进行分析。PICUs中产ESBL肠杆菌科细菌的出现和传播是少数流行菌株克隆传播以及耐药基因携带质粒在细菌间水平传播的结果。