Saps Miguel, Slivka Adam, Khan Seema, Meza Manuel P, Goyal Alka, Di Lorenzo Carlo
Division of Pediatric Gastroenterology, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.
Dig Dis Sci. 2003 Sep;48(9):1701-4. doi: 10.1023/a:1025595024344.
A 4-month-old boy presented with 9 days of abdominal distension. The abdomen was tense, distended, and nontender, with a fluid wave. Hypoalbuminemia, hyponatremia, high lipase, normal amylase, high ascitic fluid: lipase, amylase, and serum-ascites albumin gradient < 1.1 were present. Abdominal CT showed large ascites, edema, and pancreatic cyst. No improvement was noted with bowel rest, TPN, albumin, furosemide, octreotide, and paracentesis. Endoscopic retrograde cholangiopancreatography showed disrupted pancreatic duct and a cyst. Pancreatic duct stenting was complicated by early outward migration of the stent and was thus ineffective. An exploratory laporatomy revealed a cyst. Cystogastrostomy resolved the pancreatitis and ascites. The patient was discharged off TPN and tolerating enteral nutrition. Pancreatic ascites is rare, producing few or no symptoms in infants. In conclusion, our patient may have had viral pancreatitis, complicated by a disrupted duct and/or ruptured pseudocyst with ascites formation. Medical management was ineffective. Surgery appears to have been curative.
一名4个月大的男婴出现腹胀9天。腹部紧张、膨隆,无压痛,有液波震颤。存在低蛋白血症、低钠血症、高淀粉酶,淀粉酶正常,腹水淀粉酶、脂肪酶升高,血清腹水白蛋白梯度<1.1。腹部CT显示大量腹水、水肿和胰腺囊肿。禁食、全胃肠外营养(TPN)、白蛋白、呋塞米、奥曲肽和腹腔穿刺均未见改善。内镜逆行胰胆管造影显示胰管中断和囊肿。胰管支架置入术因支架早期向外移位而失败,因此无效。剖腹探查发现一个囊肿。囊肿胃吻合术解决了胰腺炎和腹水问题。患者停用TPN并能耐受肠内营养后出院。胰腺腹水罕见,在婴儿中很少产生症状或不产生症状。总之,我们的患者可能患有病毒性胰腺炎,并发胰管中断和/或假性囊肿破裂并形成腹水。内科治疗无效。手术似乎治愈了疾病。