Walker C P, Richmond N D, Lambert G D
Regional Medical Physics Department, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom.
Med Dosim. 2003 Fall;28(3):149-54. doi: 10.1016/S0958-3947(03)00065-7.
Installation of a modern high-energy Siemens Primus linear accelerator at the Northern Centre for Cancer Treatment (NCCT) provided the opportunity to investigate the optimal clinical implementation of the Siemens virtual wedge filter. Previously published work has concentrated on the production of virtual wedge angles at 15 degrees, 30 degrees, 45 degrees, and 60 degrees as replacements for the Siemens hard wedges of the same nominal angles. However, treatment plan optimization of the dose distribution can be achieved with the Primus, as its control software permits the selection of any virtual wedge angle from 15 degrees to 60 degrees in increments of 1 degrees. The same result can also be produced from a combination of open and 60 degrees wedged fields. Helax-TMS models both of these modes of virtual wedge delivery by the wedge angle and the wedge fraction methods respectively. This paper describes results of timing studies in the planning of optimized patient dose distributions by both methods and in the subsequent treatment delivery procedures. Employment of the wedge fraction method results in the delivery of small numbers of monitor units to the beam's central axis; therefore, wedge profile stability and delivered dose with low numbers of monitor units were also investigated. The wedge fraction was proven to be the most efficient method when the time taken for both planning and treatment delivery were taken into consideration, and is now used exclusively for virtual wedge treatment delivery in Newcastle. It has also been shown that there are no unfavorable dosimetric consequences from its practical implementation.
在北方癌症治疗中心(NCCT)安装一台现代高能西门子Primus直线加速器,为研究西门子虚拟楔形滤过器的最佳临床应用提供了契机。此前发表的研究主要集中在生成15度、30度、45度和60度的虚拟楔形角,以替代相同标称角度的西门子硬楔形滤过器。然而,利用Primus可以实现剂量分布的治疗计划优化,因为其控制软件允许以1度的增量选择15度至60度之间的任何虚拟楔形角。开放野和60度楔形野的组合也能产生相同的结果。Helax-TMS分别通过楔形角法和楔形分数法对这两种虚拟楔形投照模式进行建模。本文描述了通过这两种方法在优化患者剂量分布规划以及后续治疗投照程序中的时间研究结果。采用楔形分数法会向射野中心轴输送少量的监测单位;因此,还研究了楔形轮廓稳定性和少量监测单位下的输出剂量。当同时考虑规划和治疗投照所需时间时,楔形分数法被证明是最有效的方法,目前在纽卡斯尔已专门用于虚拟楔形治疗投照。研究还表明,其实际应用不会产生不利的剂量学后果。