Egorova E F, Chernoiarova O D, Ryzhkova G I
Eksp Klin Farmakol. 1992 May-Jun;55(3):39-41.
The authors provide the data on in vitro experimental studies into the pharmacological properties of protease inhibitor obtained from bovine pancreas. It is shown that the preparation exerts an inhibitory action on pancreatic proteolytic enzymes such as trypsin, kallikrein, and elastase, drastically reduces the total proteolytic activity in pancreatic tissue homogenates. Comparison with the protease inhibitor gordox has demonstrated the inhibitory effect of both preparations to be practically similar.
作者提供了关于从牛胰腺获得的蛋白酶抑制剂药理特性的体外实验研究数据。结果表明,该制剂对胰蛋白酶、激肽释放酶和弹性蛋白酶等胰腺蛋白水解酶具有抑制作用,能大幅降低胰腺组织匀浆中的总蛋白水解活性。与蛋白酶抑制剂戈尔道克斯的比较表明,两种制剂的抑制效果实际上相似。