Nieto A, Sánchez M J, Martínez C, Castellsagué X, Quintana M J, Bosch X, Conde M, Muñoz N, Herrero R, Franceschi S
Departamento de Ciencias Sociosanitarias, Facultad de Medicina, Universidad de Sevilla, Avda. Sánchez Pizjuan S/n, 41009 Sevilla, Spain.
Br J Cancer. 2003 Nov 3;89(9):1667-71. doi: 10.1038/sj.bjc.6601347.
The influence of body mass index (BMI) on oral cancer risk was evaluated in 375 incident cases and 375 age-gender-matched hospital-based controls. Low BMIs at diagnosis and 2 years before diagnosis were associated with significantly elevated odds ratios (OR for BMI < or =22 vs >26 kg m(-2); 3.64; 95% confidence interval, CI: 2.27-5.82 and 3.31; 95% CI: 2.04-5.39, respectively). The association with low BMI, however, tended to be weaker and nonsignificant among never smokers and never drinkers.
在375例新发病例和375例年龄、性别匹配的医院对照中评估了体重指数(BMI)对口腔癌风险的影响。诊断时及诊断前2年的低BMI与显著升高的比值比相关(BMI≤22 kg/m² 与>26 kg/m² 相比的比值比;分别为3.64;95%置信区间,CI:2.27 - 5.82和3.31;95%CI:2.04 - 5.39)。然而,在从不吸烟者和从不饮酒者中,与低BMI的关联往往较弱且无统计学意义。