Slart R H J A, Poot L, Piers D A, van Veldhuisen D J, Jager P L
Department of Nuclear Medicine, University Hospital Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.
Int J Cardiovasc Imaging. 2003 Oct;19(5):401-7. doi: 10.1023/a:1025817731965.
In comparison with planar imaging gated blood-pool single photon emission computed tomography (GBPS) has the advantage of separating left and right ventricle. The purpose of this investigation was to evaluate the right ventricular ejection fraction (RVEF) calculations by GBPS software ('NuSMUGA', Northwestern University, Chicago, IL) in comparison to first-pass radionuclide angiography (FPRNA).
In 22 consecutive patients FPRNA and GBPS acquisition was performed. GBPS RVEF calculations were manually and automatically performed, using all gated short-axis-slices of the right ventricle.
Automatic RVEF assessed by GBPS did not correlate with conventional FPRNA (r = 0.40, p = 0.065). Mean FPRNA RVEF was 55 +/- 10% and mean GBPS automatic RVEF was 32 +/- 8%. Also manual GBPS RVEF did not correlate with conventional FPRNA (r = 0.41, p = 0.055). Mean RVEF measurement by manual GBPS was 33 +/- 8%. Manual GBPS RVEF values correlated well with automatically determined GBPS RVEF values (r = 0.96, p < 0.0001).
Automatic and manual values RVEF values assessed by GBPS did not correlate with conventional FPRNA values. FPRNA and GBPS calculations cannot be considered to be equivalent. Therefore the NuSMUGA program cannot be used to calculate RVEF.
与平面成像相比，门控心血池单光子发射计算机断层扫描（GBPS）具有分离左右心室的优势。本研究的目的是评估GBPS软件（“NuSMUGA”，美国伊利诺伊州芝加哥西北大学）计算的右心室射血分数（RVEF）与首次通过放射性核素血管造影（FPRNA）相比的情况。
对22例连续患者进行了FPRNA和GBPS采集。使用右心室所有门控短轴切片手动和自动进行GBPS RVEF计算。
GBPS评估的自动RVEF与传统FPRNA不相关（r = 0.40，p = 0.065）。平均FPRNA RVEF为55±10%，平均GBPS自动RVEF为32±8%。手动GBPS RVEF也与传统FPRNA不相关（r = 0.41，p = 0.055）。手动GBPS测量的平均RVEF为33±8%。手动GBPS RVEF值与自动确定的GBPS RVEF值相关性良好（r = 0.96，p < 0.0001）。
GBPS评估的自动和手动RVEF值与传统FPRNA值不相关。FPRNA和GBPS计算不能被认为是等效的。因此，NuSMUGA程序不能用于计算RVEF。
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