卡普霉素类似物的合成及抗分枝杆菌活性。第2部分：卡普霉素相关化合物的酰化衍生物
Synthesis and antimycobacterial activity of capuramycin analogues. Part 2: acylated derivatives of capuramycin-related compounds.
作者信息
Hotoda Hitoshi, Daigo Makiko, Furukawa Miyuki, Murayama Kazuhiro, Hasegawa Chikako Akiyama, Kaneko Masakatsu, Muramatsu Yasunori, Ishii Michiko Miyazawa, Miyakoshi Shun-ichi, Takatsu Toshio, Inukai Masatoshi, Kakuta Masayo, Abe Tomomi, Fukuoka Takashi, Utsui Yukio, Ohya Satoshi
机构信息
Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.
出版信息
Bioorg Med Chem Lett. 2003 Sep 1;13(17):2833-6. doi: 10.1016/s0960-894x(03)00597-3.
Abstract
Acylated derivatives of capuramycin and A-500359A were synthesized and tested for antimycobacterial activity. Compound 20 having a decanoyl group showed very potent activity.
摘要
合成了卡普霉素和A-500359A的酰化衍生物，并测试了它们的抗分枝杆菌活性。具有癸酰基的化合物20表现出非常强的活性。
Zotero 插件