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[Oral lichen planus and liver pathology. II. The clinico-statistical correlations between oral manifestations and liver damage].

作者信息

Gandolfo S, Carbone M, Zulian P, Broccoletti R, Carrozzo M

机构信息

Clinica Odontostomatologica, Università degli Studi di Torino.

出版信息

Minerva Stomatol. 1992 May;41(5):209-13.

PMID:1461243
Abstract

To characterize with more precision the association between oral lichen planus (OLP) and hepatopathies, 96 patients with OLP were separated in two groups ordered by presence or absence of liver diseases comparing some variables (age, sex, presence of pain, clinical variety, presence of skin lesions, alcohol consumption and exposure to drugs inducing hepatic injury) and evaluating the statistical significance. Factors associated with increased frequency of liver diseases were erosive variety of OLP (p = 0.024) and presence of pain (p = 0.026) (chi square test with Yates correction). It's confirmed that OLP patients with higher risk of liver disease are those that have erosive lesions with severe symptoms and often diffused in the entire oral cavity; furthermore, it's highlighted that the probability to find liver disease associated with reticular and plaque-like form of OLP is low, but not negligible.

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