McClay John E, Murray Alan D, Booth Tim
Department of Otolaryngology-Head and Neck Surgery, University of Texas at Southwestern Medical School and Children's Hospital of Dallas, 73235, USA.
Arch Otolaryngol Head Neck Surg. 2003 Nov;129(11):1207-12. doi: 10.1001/archotol.129.11.1207.
To determine the effectiveness of using intravenous antibiotics alone to treat clinically stable children with clearly defined deep neck abscesses diagnosed by contrast-enhanced computed tomography (CT).
Retrospective chart and CT scan review.
Tertiary care children's hospital.
The study comprised clinically stable pediatric patients who presented with signs and symptoms of a deep neck infection and who had CT scans demonstrating an abscess in the parapharyngeal space, retropharyngeal space, or both that included (1) a well-formed ring enhancement around a nonenhancing density consistent with fluid and (2) a size greater than 1 cm in every dimension.
Clinical resolution of the signs and symptoms of the deep neck abscess after treatment with intravenous antibiotics.
Over a 22-month period (May 1999 to March 2001), 11 children ranging in age from 4 months to 16(1/2) years who had contrast-enhanced CT evidence of deep neck abscess and no clinical evidence of severe symptoms or significant airway compromise were initially treated with intravenous antibiotics. Ten (91%) of the 11 children responded to intravenous antibiotic therapy as their only treatment. All 10 responders began to improve clinically by 48 hours. The symptoms resolved in 5 children by treatment day 3. Five to 8 days of treatment were required to completely resolve the symptoms in the other 5 patients. The 1 child who did not respond to intravenous antibiotic therapy underwent surgical drainage of her deep neck abscess within 12 hours of admission, with purulence discovered at the time of surgery.
In a select number of clinically stable children, deep neck abscesses diagnosed on contrast-enhanced CT scans using strict radiographic criteria can be effectively treated with intravenous antibiotics alone.
确定单独使用静脉抗生素治疗经增强计算机断层扫描(CT)明确诊断为深部颈部脓肿的临床稳定儿童的有效性。
回顾性病历及CT扫描复查。
三级儿童专科医院。
本研究纳入了临床稳定的儿科患者,这些患者出现深部颈部感染的体征和症状,且CT扫描显示咽旁间隙、咽后间隙或两者均有脓肿,包括(1)在与液体一致的无强化密度周围有完整的环形强化,(2)各维度尺寸大于1厘米。
静脉抗生素治疗后深部颈部脓肿体征和症状的临床缓解情况。
在22个月期间(1999年5月至2001年3月),11名年龄在4个月至16(1/2)岁之间的儿童经增强CT证实有深部颈部脓肿,且无严重症状或明显气道受压的临床证据,最初接受静脉抗生素治疗。11名儿童中有10名(91%)仅接受静脉抗生素治疗有效。所有10名有反应的儿童在48小时内开始临床改善。5名儿童在治疗第3天时症状缓解。另外5名患者需要5至8天的治疗才能完全缓解症状。1名对静脉抗生素治疗无反应的儿童在入院后12小时内接受了深部颈部脓肿的手术引流,手术时发现有脓性分泌物。
在部分临床稳定的儿童中,根据严格的影像学标准经增强CT扫描诊断的深部颈部脓肿,单独使用静脉抗生素即可有效治疗。