Microwave-assisted synthesis utilizing supported reagents: a rapid and efficient acylation procedure.
作者信息
Sauer Daryl R, Kalvin Douglas, Phelan Kathleen M
机构信息
High-Throughput Organic Synthesis Group, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064-6113, USA.
出版信息
Org Lett. 2003 Nov 27;5(24):4721-4. doi: 10.1021/ol0358915.
PMID:14627424
Abstract
[reaction: see text] The application of microwave heating to a polymer-assisted solution-phase (PASP) synthesis technique has been utilized to develop a rapid and efficient protocol for the solution-phase synthesis of amides from either amine or carboxylic acid cores.
摘要
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