[Course of pregnancy and labor after prenatal diagnosis of genetic defects and abnormalities].

138 patients were referred to us to prenatal diagnosis of genetic defects. Only in 120 patients the diagnostic procedures could also be carried out. In 75% the amniocentesis was performed to establish the amnion cell culture and in 22.5% for analysis of alphafetoprotein and for performance of fetography. In 4.2% a genetic indication for interruption was found by the prenatal diagnosis. Among the 61 terminated pregnancies a premature delivery occurred in 13.1%. The operating frequency of delivery was 16.2% and the perinatal mortality was 1.6%.