一名年轻的原发性血小板增多症女性患者经血小板单采术治疗后成功妊娠。

Successful pregnancy in a young woman with essential thrombocythemia treated with platelet apheresis.

作者信息

Relakis C, Kyriakou D, Makrigiannakis A S, Kalokyri I, Datseris G, Coumantakis E, Eliopoulos G D

机构信息

Department of Obstetrics and Gynecology of the University of Crete School of Medicine, University Hospital of Heraklion, Crete, Greece.

出版信息

Haematologia (Budap). 1996;27(4):197-200.

PMID:14651220

Abstract

We report a 27-year-old woman with essential thrombocythemia who had delivered a healthy baby after Caesarian section. The patient was treated with two courses of platelet apheresis at the beginning of the gestation. Subsequent to this procedure, the platelet count decreased progressively and remained at about 500,000/microl of blood until delivery without any further treatment. Caesarian section was performed at the 37th week when the placenta presented grade III lesions on ultrasound examination. Histology of the placenta revealed multiple infarcts. Platelet count in the newborn was normal. We concluded that essential thrombocythemia is not a risk factor for pregnancy, and that platelet count may decrease during pregnancy. In addition, an emergent reduction of platelets may easily be obtained by platelet apheresis.

摘要

我们报告了一名27岁患有原发性血小板增多症的女性，她在剖宫产术后产下了一名健康的婴儿。该患者在妊娠初期接受了两个疗程的血小板单采治疗。在此治疗后，血小板计数逐渐下降，并在未进行任何进一步治疗的情况下一直维持在约500,000/微升血液，直至分娩。在妊娠37周时进行了剖宫产，当时超声检查显示胎盘呈现III级病变。胎盘组织学检查显示有多处梗死。新生儿的血小板计数正常。我们得出结论，原发性血小板增多症不是妊娠的危险因素，并且血小板计数在妊娠期间可能会下降。此外，通过血小板单采可以轻松实现血小板的紧急减少。