Dawn Buddhadeb, Talley J David, Prince Charles R, Hoque Azizul, Morris Glenn T, Xenopoulos Nicholaos P, Stoddard Marcus F
Department of Medicine, University of Louisville and Jewish Hospital Heart and Lung Institute, KY 40292, USA.
J Am Soc Echocardiogr. 2003 Dec;16(12):1274-86. doi: 10.1067/S0894-7317(03)00554-6.
The purpose of this study was to examine the use of transesophageal echocardiography (TEE) in the identification and flow characterization of congenital coronary anomalies.
Congenital coronary anomalies in adults are rare but may cause serious cardiac complications. The use of TEE in evaluation of this entity has not been well defined. Very little is known regarding flow patterns in anomalous coronaries assessed by Doppler TEE.
A total of 32 consecutive adult patients were studied using TEE to define the origin, course, and proximal flow pattern of suspected coronary anomalies.
Coronary anomalies identified using TEE included anomalous origin from the pulmonary trunk (n = 2), right sinus (n = 18), left sinus (n = 9), single coronary (n = 2), and left main coronary fistula (n = 1). Multiplane TEE performed in 20 cases simplified the delineation of more complex coronary anomalies. The origin was identified in all patients, proximal course delineated in 31, and proximal flow pattern characterized by pulsed Doppler in 23 of 32 patients. In 16 anomalous left main, left anterior descending, or left circumflex coronary arteries, an abnormal systolic flow pattern (ie, systolic/diastolic time-velocity integral ratio >1) occurred exclusively (P <.001) when the anomalous artery had an intermediate (100%; 5/5) versus anterior or posterior course (0%; 0/11) relative to the aortic and pulmonary artery trunks. A systolic flow pattern was also evident in 4 (80%) of 5 patients with an anomalous right coronary artery with an intermediate course.
TEE, particularly with a multiplane probe, has an important complementary role to coronary angiography in delineating the proximal course and pattern of flow in anomalous coronaries. Predominant systolic flow pattern in anatomically left proximal anomalous coronaries signifies an intermediate course between the aorta and the pulmonary trunk and may be clinically useful for risk stratification.
本研究旨在探讨经食管超声心动图(TEE)在先天性冠状动脉异常的识别及血流特征描述中的应用。
成人先天性冠状动脉异常较为罕见,但可能导致严重的心脏并发症。TEE在评估该疾病中的应用尚未明确界定。关于经多普勒TEE评估的异常冠状动脉血流模式,人们知之甚少。
连续对32例成年患者进行TEE检查,以明确疑似冠状动脉异常的起源、走行及近端血流模式。
通过TEE识别出的冠状动脉异常包括起源于肺动脉干(n = 2)、右窦(n = 18)、左窦(n = 9)、单冠状动脉(n = 2)以及左冠状动脉主干瘘(n = 1)。20例患者进行了多平面TEE检查,简化了对更复杂冠状动脉异常的描绘。所有患者的冠状动脉起源均得以确定,31例患者的近端走行得以描绘,32例患者中有23例通过脉冲多普勒对近端血流模式进行了特征描述。在16例异常的左冠状动脉主干、左前降支或左旋支中,当异常动脉相对于主动脉和肺动脉干呈中间走行时(100%;5/5),与呈前或后走行时(0%;0/11)相比,出现了异常的收缩期血流模式(即收缩期/舒张期时间 - 速度积分比值>1)(P <.001)。在5例呈中间走行的异常右冠状动脉患者中,有4例(80%)也出现了收缩期血流模式。
TEE,尤其是使用多平面探头时,在描绘异常冠状动脉的近端走行和血流模式方面对冠状动脉造影具有重要的补充作用。解剖学上位于左近端的异常冠状动脉中主要的收缩期血流模式表明其在主动脉和肺动脉干之间呈中间走行,可能对临床风险分层具有实用价值。