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[肿瘤标志物癌抗原125和肿瘤相关胰蛋白酶抑制剂在宫颈癌和子宫癌患者中的意义]

[Significance of the the tumor markers, Ca-125 and tumor-associated trypsin inhibitor in patients with carcinoma of the cervix and uterus].

作者信息

Ilić R S, Mihailović D

机构信息

Department of Pathology, University Clinical Centre, Nis.

出版信息

Srp Arh Celok Lek. 1992 Mar-Apr;120(3-4):97-9.

PMID:1465666
Abstract

Quantitative contents of tumour markers in 51 patient suffering from carcinomas of the cervix and corpus uteri, are analysed. CA-125 and tumor-associated-trypsin-inhibitor (TATI) were determined in the serum of these patients before and after surgical treatment. After careful and detailed analysis and statistical testing of the results, we observed insignificant changes of CA-125 in both localisations of carcinoma. The great importance of preoperative determination of TATI markers in carcinomas of the corpus uteri is emphasized. However, the testing of these markers should be performed with great attention and in correlation with other indexes of pathobiological nature of cancers of the cervix and corpus uteri.

摘要

分析了51例子宫颈癌和子宫体癌患者肿瘤标志物的定量含量。在手术治疗前后测定了这些患者血清中的CA - 125和肿瘤相关胰蛋白酶抑制剂(TATI)。经过对结果的仔细详细分析和统计检验,我们观察到在两种癌的定位中CA - 125的变化不显著。强调了术前测定子宫体癌中TATI标志物的重要性。然而,这些标志物的检测应格外谨慎,并与子宫颈癌和子宫体癌的其他病理生物学性质指标相关联进行。

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