Leslie Kate, Sessler Daniel I
Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Parkville, Vic. 3050, Australia.
Best Pract Res Clin Anaesthesiol. 2003 Dec;17(4):485-98. doi: 10.1016/s1521-6896(03)00049-1.
Perioperative hypothermia is common in high-risk surgical patients. Anaesthesia impairs central thermoregulation, allowing re-distribution of body heat. Cool ambient temperatures and high-volume fluid administration accelerate loss of heat to the environment. Randomized, controlled trials have proven that mild hypothermia increases the incidence of wound infection and prolongs hospitalization, increases the incidence of morbid cardiac events and ventricular tachycardia, and impairs coagulation. Other complications include enhanced anaesthetic drugs effects, prolonged recovery room stays, shivering, and impaired immune function. There is compelling animal evidence for cerebral protection by mild hypothermia. However, evidence for protection in surgical patients is not yet available. The most effective means of preventing perioperative hypothermia is active pre-warming. High ambient temperatures, warmed intravenous fluids and active cutaneous warming are useful intra-operatively, while active cutaneous warming and intravenous pethidine abolish post-operative shivering. Proper thermal management may reduce complications and improve the outcome in high-risk surgical patients.
围手术期体温过低在高危手术患者中很常见。麻醉会损害中枢体温调节功能,导致身体热量重新分布。凉爽的环境温度和大量输液会加速热量散失到环境中。随机对照试验已证明,轻度体温过低会增加伤口感染的发生率并延长住院时间,增加心脏不良事件和室性心动过速的发生率,并损害凝血功能。其他并发症包括麻醉药物作用增强、恢复室停留时间延长、寒战和免疫功能受损。有确凿的动物证据表明轻度体温过低对大脑有保护作用。然而,目前尚无手术患者中保护作用的证据。预防围手术期体温过低的最有效方法是主动预热。较高的环境温度、温热的静脉输液和主动皮肤加温在术中很有用,而主动皮肤加温和静脉注射哌替啶可消除术后寒战。适当的体温管理可以减少高危手术患者的并发症并改善预后。