Dong Xiaoguang, Yu Bin, Xie Lixin
From Shandong Eye Institute and Hospital, Qingdao, China.
J Cataract Refract Surg. 2003 Nov;29(11):2168-73. doi: 10.1016/s0886-3350(03)00668-0.
To evaluate the efficacy of secondary black diaphragm intraocular lens (IOL) implantation in aphakic eyes with traumatic aniridia and previous pars plana vitrectomy (PPV).
Shandong Eye Institute and Hospital, Qingdao, China.
This retrospective study comprised 15 aphakic eyes with aniridia and no vitreous that had implantation of a secondary black diaphragm IOL 6 to 72 months after PPV. The PPV was performed as a result of trauma to the posterior segment. Before implantation of the IOL, all patients had reduced visual acuity from aphakia and intolerable glare from aniridia. Eyes were aphakic as a result of previous extracapsular cataract extraction (1 eye), lens extrusion during trauma (3 eyes), or simultaneous cataract lensectomy during PPV (11 eyes). Significant iris defects were present, with 9 eyes being aniridic after the injury. The mean follow-up was 17 months (range 3 to 34 months). The postoperative visual acuity, intra- ocular pressure (IOP), endothelial cell density, IOL centration, and intraocular inflammation were monitored.
All 15 eyes had improved visual acuity and marked glare reduction after IOL implantation. No major IOL decentration was seen. Five patients had increased IOP 3 to 5 days after IOL implantation; 3 were known to have secondary glaucoma from trauma before surgery and their IOP was controlled preoperatively (< 21 mm Hg) with timolol 0.5% eyedrops. The other 2 patients had normal- appearing angles, and 1 was diagnosed with hemolytic glaucoma after IOL insertion. Postoperative elevated IOP was controlled by timolol eyedrops (4 eyes) or selective laser trabeculoplasty (1 eye). Hyphema was seen in 1 patient on the first day after IOL implantation, but no further bleeding was noted. Vitreous hemorrhage was seen the first day after IOL insertion in 2 patients. One resolved without sequelae; the other required vitreous washout. Retinal detachment and cystoid macular edema did not occur in any patient.
Black diaphragm IOL implantation can be considered in eyes with coexisting aphakia and aniridia and without vitreous. Intraoperative IOP regulation is crucial in vitrectomized eyes to prevent complications such as expulsive hemorrhage. In general, visual function was better after IOL insertion as a result of better visual acuity and glare reduction. Although this IOL appears to be safe, long-term results must be assessed in studies with a longer follow-up and a larger study group.
评估二期植入带虹膜隔人工晶状体(IOL)在有外伤性无虹膜且既往行过玻璃体切割术(PPV)的无晶状体眼中的疗效。
中国青岛山东眼科研究所及医院。
本回顾性研究纳入了15例无虹膜且无玻璃体的无晶状体眼,这些眼在PPV术后6至72个月植入了二期带虹膜隔IOL。PPV是因眼后段外伤而进行的。在植入IOL之前,所有患者均因无晶状体导致视力下降,且因无虹膜而有无法耐受的眩光。这些眼无晶状体的原因分别为既往行白内障囊外摘除术(1眼)、外伤时晶状体脱位(3眼)或PPV术中同时行晶状体切除术(11眼)。存在明显的虹膜缺损,9眼外伤后为无虹膜。平均随访时间为17个月(范围3至34个月)。监测术后视力、眼压(IOP)、内皮细胞密度、IOL中心定位及眼内炎症情况。
所有15眼植入IOL后视力均有提高,眩光明显减轻。未见IOL明显偏心。5例患者在IOL植入后3至5天眼压升高;其中3例术前已知因外伤继发青光眼,术前使用0.5%噻吗洛尔滴眼液眼压得到控制(<21 mmHg)。另外2例患者房角外观正常,其中1例在IOL植入后被诊断为溶血性青光眼。术后眼压升高通过噻吗洛尔滴眼液(4眼)或选择性激光小梁成形术(1眼)得到控制。1例患者在IOL植入后第1天出现前房积血,但未再出现出血。2例患者在IOL植入后第1天出现玻璃体积血。1例自行吸收,无后遗症;另1例需要进行玻璃体冲洗。所有患者均未发生视网膜脱离和黄斑囊样水肿。
对于并存无晶状体和无虹膜且无玻璃体的眼,可考虑植入带虹膜隔IOL。在玻璃体切除的眼中,术中眼压调控对于预防诸如驱逐性出血等并发症至关重要。总体而言,植入IOL后由于视力提高和眩光减轻,视觉功能更好。尽管这种IOL似乎是安全的,但必须在随访时间更长、研究组更大的研究中评估长期结果。