格雷夫斯病与肺动脉高压：2例报告
Graves' disease and pulmonary hypertension: report of 2 cases.
作者信息
Virani Salim S, Mendoza Cesar E, Ferreira Alexandre C, de Marchena Eduardo
机构信息
Division of Cardiology, Jackson Memorial Hospital, University of Miami School of Medicine, Miami, Florida 33136, USA.
出版信息
Tex Heart Inst J. 2003;30(4):314-5.
Abstract
A possible association between hyperthyroidism and pulmonary hypertension has been reported. We describe 2 patients who had pulmonary hypertension associated with Graves' disease, both of whom experienced prompt hemodynamic and symptomatic recovery after normal thyroid function was restored. An autoimmune mechanism associated with vascular endothelial damage appears to have played a key pathogenic role in the development of pulmonary hypertension in these patients.
摘要
甲状腺功能亢进与肺动脉高压之间可能存在关联，这一情况已有报道。我们描述了2例患有与格雷夫斯病相关的肺动脉高压的患者，这两位患者在甲状腺功能恢复正常后，血液动力学和症状均迅速恢复。与血管内皮损伤相关的自身免疫机制似乎在这些患者肺动脉高压的发展过程中起到了关键的致病作用。
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