Farmery A D, Shlugman D, Rahman R, Rosen P
Oxford Eye Hospital, Department of Anaesthetics, Oxford, UK.
Eur J Anaesthesiol. 2003 Dec;20(12):973-8. doi: 10.1017/s0265021503001571.
We compared the effects of sub-Tenon's local anaesthetic block and placebo on peri-operative opioid requirement and cardiovascular stability and on postoperative pain, nausea and vomiting in patients undergoing vitreo-retinal surgery under general anaesthesia.
We studied 43 patients undergoing vitreo-retinal surgery under general anaesthesia in a randomized double blind study. Patients received a standard general anaesthetic followed by a sub-Tenon's injection of 4-5 mL of either bupivacaine 0.75% or saline. We recorded intraoperative invasive arterial pressure, then the incidence and severity of pain and of nausea and vomiting, for 24 h postoperatively.
In the sub-Tenon's bupivacaine group, there was a significant reduction in the perioperative opioid use and a reduction in the frequency of bradycardia and hypertensive episodes, defined as a rise > 25% of baseline for a duration of > 3 min. The sub-Tenon's bupivacaine group also had significantly lower pain scores and nausea scores at 12 h, concomitant with a lower consumption of analgesia and antiemetics.
This local anaesthetic technique is effective in vitreo-retinal surgery and can be safely applied to this population of patients regardless of axial length.
我们比较了球后局部麻醉阻滞和安慰剂对全身麻醉下玻璃体视网膜手术患者围手术期阿片类药物需求、心血管稳定性以及术后疼痛、恶心和呕吐的影响。
我们在一项随机双盲研究中对43例接受全身麻醉的玻璃体视网膜手术患者进行了研究。患者接受标准全身麻醉,随后在球后注射4 - 5毫升0.75%布比卡因或生理盐水。我们记录了术中有创动脉压,以及术后24小时疼痛、恶心和呕吐的发生率及严重程度。
在球后布比卡因组,围手术期阿片类药物使用显著减少,心动过缓和高血压发作频率降低,高血压发作定义为血压较基线升高>25%且持续时间>3分钟。球后布比卡因组在术后12小时的疼痛评分和恶心评分也显著更低,同时镇痛和止吐药物的消耗量也更低。
这种局部麻醉技术在玻璃体视网膜手术中有效,且无论眼轴长度如何,均可安全应用于这类患者群体。