[血液制品白细胞过滤的质量控制]

[Quality control of leukocyte filtration of blood products].

作者信息

Flesland O, Solheim B G

机构信息

Røde Kors og Rikshospitalets Blodsenter, Oslo.

出版信息

Tidsskr Nor Laegeforen. 1992 Oct 10;112(24):3090-1.

PMID:1471084

Abstract

Quality control of leucocyte depleted blood products has become a problem since the introduction of bedside leucocyte filtration. At our Blood Centre, this problem has been circumvented by testing a sample taken as the filtration is completed by sealing off a 10 cm piece of tubing just under the filter. We have tested four brands of erythrocyte filters, Pall RC100, Erypur Optima b, Sepacell R-200A and Sepacell R-500A(II) using two erythrocyte concentrates for each filter. We have tested two brands of thrombocyte filters, Pall PL100 with 6-8 thrombocyte concentrates, and Sepacell PL-5A with 2-6 concentrates. No transfusion should give more than 5 x 10(6) leucocytes. Pall PL100, Pall RC100 and Sepacell R-500A(II) met the criteria.

摘要

自从采用床边白细胞过滤以来，白细胞去除血液制品的质量控制就成了一个问题。在我们的血液中心，通过在过滤器下方密封一段10厘米长的管道，在过滤完成时采集样本进行检测，这个问题得以解决。我们使用两种红细胞浓缩液对四种品牌的红细胞过滤器（颇尔RC100、Erypur Optima b、Sepacell R - 200A和Sepacell R - 500A(II)）进行了测试。我们还对两种品牌的血小板过滤器进行了测试，即使用6 - 8份血小板浓缩液的颇尔PL100和使用2 - 6份浓缩液的Sepacell PL - 5A。任何一次输血所输入的白细胞不应超过5×10⁶个。颇尔PL100、颇尔RC100和Sepacell R - 500A(II)符合标准。