Hillis Susan D, Anda Robert F, Dube Shanta R, Felitti Vincent J, Marchbanks Polly A, Marks James S
National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
Pediatrics. 2004 Feb;113(2):320-7. doi: 10.1542/peds.113.2.320.
Few reports address the impact of cumulative exposure to childhood abuse and family dysfunction on teen pregnancy and consequences commonly attributed to teen pregnancy. Therefore, we examined whether adolescent pregnancy increased as types of adverse childhood experiences (ACE score) increased and whether ACEs or adolescent pregnancy was the principal source of elevated risk for long-term psychosocial consequences and fetal death.
DESIGN, SETTING, AND PARTICIPANTS: A retrospective cohort study of 9159 women aged > or = 18 years (mean 56 years) who attended a primary care clinic in San Diego, California in 1995-1997.
Adolescent pregnancy, psychosocial consequences, and fetal death, compared by ACE score (emotional, physical, or sexual abuse; exposure to domestic violence, substance abusing, mentally ill, or criminal household member; or separated/divorced parent).
Sixty-six percent (n = 6015) of women reported > or = 1 ACE. Teen pregnancy occurred in 16%, 21%, 26%, 29%, 32%, 40%, 43%, and 53% of those with 0, 1, 2, 3, 4, 5, 6, and 7 to 8 ACEs. As the ACE score rose from zero to 1 to 2, 3 to 4, and > or = 5, odds ratios for each adult consequence increased (family problems: 1.0, 1.5, 2.2, 3.3; financial problems: 1.0, 1.6, 2.3, 2.4; job problems: 1.0, 1.4, 2.3, 2.9; high stress: 1.0, 1.4, 1.9, 2.2; and uncontrollable anger: 1.0, 1.6, 2.8, 4.5, respectively). Adolescent pregnancy was not associated with any of these adult outcomes in the absence of childhood adversity (ACEs: 0). The ACE score was associated with increased fetal death after first pregnancy (odds ratios for 0, 1-2, 3-4, and 5-8 ACEs: 1.0, 1.2, 1.4, and 1.8, respectively); teen pregnancy was not related to fetal death.
The relationship between ACEs and adolescent pregnancy is strong and graded. Moreover, the negative psychosocial sequelae and fetal deaths commonly attributed to adolescent pregnancy seem to result from underlying ACEs rather than adolescent pregnancy per se.
很少有报告探讨童年期虐待和家庭功能障碍的累积暴露对青少年怀孕以及通常归因于青少年怀孕的后果的影响。因此,我们研究了随着不良童年经历类型(ACE 评分)增加青少年怀孕是否增加,以及 ACEs 或青少年怀孕是否是长期心理社会后果和胎儿死亡风险升高的主要来源。
设计、设置和参与者:一项对 9159 名年龄≥18 岁(平均 56 岁)女性的回顾性队列研究,这些女性于 1995 - 1997 年在加利福尼亚州圣地亚哥的一家初级保健诊所就诊。
按 ACE 评分(情感、身体或性虐待;暴露于家庭暴力、滥用药物、患有精神疾病或有犯罪家庭成员;或父母分居/离婚)比较青少年怀孕、心理社会后果和胎儿死亡情况。
66%(n = 6015)的女性报告有≥1 次 ACE。在 ACE 评分为 0、1、2、3、4、5、6 以及 7 - 8 次的女性中,青少年怀孕发生率分别为 16%、21%、26%、29%、32%、40%、43%和 53%。随着 ACE 评分从 0 升至 1 至 2、3 至 4 以及≥5,每种成人后果的比值比均增加(家庭问题:1.0、1.5、2.2、3.3;经济问题:1.0、1.6、2.3、2.4;工作问题:1.0、1.4、2.3、2.9;高压力:1.0、1.4、1.9、2.2;以及无法控制的愤怒:1.0、1.6、2.8、4.5)。在没有童年逆境(ACEs:0)的情况下,青少年怀孕与这些成人后果均无关联。ACE 评分与首次怀孕后的胎儿死亡增加相关(ACE 评分为 0、1 - 2、3 - 4 和 5 - 8 次的比值比分别为 1.0、1.2、1.4 和 1.8);青少年怀孕与胎儿死亡无关。
ACEs 与青少年怀孕之间的关系紧密且呈梯度变化。此外,通常归因于青少年怀孕的负面心理社会后遗症和胎儿死亡似乎是由潜在的 ACEs 导致,而非青少年怀孕本身。