Rosenzweig Ted
Department of General Surgery, Alaska Native Medical Center, Anchorage, Alaska 99508, USA.
Int J Circumpolar Health. 2003 Dec;62(4):388-96. doi: 10.3402/ijch.v62i4.17582.
The expected rate of deep vein thrombosis (DVT) after laparotomy or major joint surgery has been reported to be 20 to 50% for unprophylaxed non-native patients. DVT prophylaxis for surgical patients at the Alaska native Medical Center has typically not been offered as the perceived rate of DVT and pulmonary embolism in our patient population has been very low. Retrospective analysis of positive venous duplex scans at our institution revealed only four cases of post-operative DVT during a two-year interval. This study was designed to document the actual rate of post-operative DVT in Alaskan natives not provided with routine DVT prophylaxis.
Prospective cohort study of DVT in open abdominal, open knee, open hip and pelvic fracture surgery patients at the Alaska native Medical Center from 1999-2001.
The day prior to expected discharge, we performed venous duplex ultrasonography on 67 patients with open abdominal surgery, major open knee or hip surgery, or pelvic fracture who received no DVT prophylaxis. Some patients included in the study were also asked questions about their consumption of marine mammals and fish, and the native blood quanta was estimated in all patients using existing data bases.
Sixty percent of the study population was determined to be at high risk for DVT using standard risk stratification methods. Dietary habits varied widely, but were largely reported as being "traditionally" native. Nearly all patients had 50% or more "native blood". Only one of 67 patients developed a documented post-operative DVT.
Post-operative deep vein thrombosis in Alaskan natives not provided with routine DVT prophylaxis is rare. The data does not provide a clear indication as to why Alaskan natives may be at decreased risk for post-operative DVT.
据报道,对于未接受预防措施的非本地患者,剖腹手术或大关节手术后深静脉血栓形成(DVT)的预期发生率为20%至50%。阿拉斯加土著医疗中心通常不为手术患者提供DVT预防措施,因为我们认为我们患者群体中DVT和肺栓塞的发生率非常低。对我们机构静脉双功超声扫描阳性结果的回顾性分析显示,在两年期间仅发现4例术后DVT病例。本研究旨在记录未接受常规DVT预防措施的阿拉斯加土著患者术后DVT的实际发生率。
对1999年至2001年阿拉斯加土著医疗中心接受开腹手术、膝关节开放手术、髋关节开放手术和骨盆骨折手术患者的DVT进行前瞻性队列研究。
在预期出院前一天,我们对67例接受开腹手术、膝关节或髋关节大手术或骨盆骨折且未接受DVT预防措施的患者进行了静脉双功超声检查。研究中纳入的一些患者还被问及食用海洋哺乳动物和鱼类的情况,并使用现有数据库估计了所有患者的本地血统比例。
使用标准风险分层方法确定,60%的研究人群处于DVT高风险。饮食习惯差异很大,但大多报告为“传统”的本地饮食习惯。几乎所有患者的“本地血统”比例达到或超过50%。67例患者中只有1例出现了有记录的术后DVT。
未接受常规DVT预防措施的阿拉斯加土著患者术后深静脉血栓形成很少见。数据并未明确表明阿拉斯加土著患者术后DVT风险降低的原因。