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治疗牙龈退缩的手术疗法。一项系统评价。

Surgical therapies for the treatment of gingival recession. A systematic review.

作者信息

Oates Thomas W, Robinson Melanie, Gunsolley John C

机构信息

Department of Periodontics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

出版信息

Ann Periodontol. 2003 Dec;8(1):303-20. doi: 10.1902/annals.2003.8.1.303.

Abstract

BACKGROUND

A variety of soft tissue augmentation procedures directed at root coverage have been documented in the literature utilizing autogenous or allogenic soft tissue grafting or guided tissue regeneration (GTR).

RATIONALE

The purpose of this systematic review was to assess the literature regarding the efficacies of various surgical gingival augmentation procedures relative to clinical and patient-oriented outcomes.

FOCUSED QUESTION

What is the effect of surgical therapy for root coverage in patients with gingival recession compared with other treatment modalities or baseline values?

SEARCH PROTOCOL

PubMed and the Cochrane Oral Health Group Trials Register were searched to identify human studies in English investigating the therapeutic use of a soft tissue surgical procedure to treat gingival recession. Searches were performed for articles published by April 2002.

SELECTION CRITERIA

Initial screening of identified abstracts accepted all studies evaluating surgical intervention of gingival recession. Independent review by 2 reviewers evaluated full-text reports regarding study characteristics. Only those studies determined to be randomized clinical trials (RCTs) were included in the final analysis. DATA ANALYSIS AND COLLECTION: Outcome measures included changes in root coverage, clinical attachment levels (CAL), probing depth (PD), and width of keratinized tissue (KT). The only data suitable for meta-analysis were comparisons of the efficacy of connective tissue grafts with GTR.

MAIN RESULTS

  1. Thirty-two articles (total study population: 687) met the criteria for RCTs: 11 (population: 286) related to various autogenous soft tissue augmentation procedures; 18 (population: 360) to GTR; and 3 (population: 41) to allogenic soft tissue augmentation. 2. Meta-analysis identified greater gains in both root coverage and keratinized tissue width for connective tissue graft procedures compared to GTR. 3. No other data were compatible with meta-analysis.

REVIEWERS' CONCLUSIONS: 1. Soft tissue augmentation procedures are effective means of obtaining root coverage. 2. Connective grafting techniques appear to have an advantage over GTR. 3. There is a need for further efficacy studies and for investigation of these procedures relative to patient-oriented outcomes such as esthetics, root sensitivity, and postoperative morbidities.

摘要

背景

文献中已记载了多种针对牙根覆盖的软组织增量手术,这些手术采用自体或异体软组织移植或引导组织再生(GTR)技术。

理论依据

本系统评价的目的是评估有关各种手术性牙龈增量手术相对于临床和以患者为导向的结局的疗效的文献。

重点问题

与其他治疗方式或基线值相比,手术治疗对牙龈退缩患者牙根覆盖的效果如何?

检索方案

检索了PubMed和Cochrane口腔健康组试验注册库,以识别用英文撰写的关于软组织手术治疗牙龈退缩的人体研究。检索截至2002年4月发表的文章。

选择标准

对所识别摘要的初步筛选接受了所有评估牙龈退缩手术干预的研究。由2名审阅者独立审查评估了关于研究特征的全文报告。最终分析仅纳入那些被确定为随机临床试验(RCT)的研究。

数据分析与收集

结局指标包括牙根覆盖、临床附着水平(CAL)、探诊深度(PD)和角化组织宽度(KT)的变化。唯一适合进行荟萃分析的数据是结缔组织移植与GTR疗效的比较。

主要结果

  1. 32篇文章(总研究人群:687例)符合RCT标准:11篇(人群:286例)与各种自体软组织增量手术有关;18篇(人群:360例)与GTR有关;3篇(人群:41例)与异体软组织增量有关。2. 荟萃分析表明,与GTR相比,结缔组织移植手术在牙根覆盖和角化组织宽度方面的增加更大。3. 没有其他数据与荟萃分析兼容。

审阅者结论

  1. 软组织增量手术是获得牙根覆盖的有效手段。2. 结缔组织移植技术似乎比GTR更具优势。3. 需要进一步进行疗效研究,并针对诸如美观、牙根敏感和术后发病率等以患者为导向的结局对这些手术进行研究。

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