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Evaluation of screening procedures for congenital cataracts.

作者信息

Magnusson G, Jakobsson P, Kugelberg U, Lundvall A, Maly E, Tornqvist K, Abrahamsson M, Andreasson B, Borres M P, Broberger U, Hellström-Westas L, Kornfält R, Nelson N, Sjöstrand J, Thiringer K

机构信息

Department of Ophthalmology, Sahlgrenska University Hospital, Göteborg, Sweden.

出版信息

Acta Paediatr. 2003 Dec;92(12):1468-73.

Abstract

AIM

To evaluate the efficacy of two different Swedish screening procedures for early detection of congenital cataracts in comparison with no screening.

METHODS

Children born between January 1992 and December 1998 in Swedish regions with an established eye-screening routine procedure, diagnosed with congenital cataract, and operated on before 1 y of age, were included in a retrospective study. Age at referral and age at time of the operation were compared between regions using different screening procedures: screening in the maternity wards (Region 1), at the well-baby clinics (Region 2) and one region without any screening (Region 3).

RESULTS

Seventy-two children were included in the study. Concerning early diagnosis and surgery, Region 1 differed significantly from Regions 2 and 3, which were more similar and were combined for further analysis. The difference in detected cases was greatest at 21 d of age (55% vs 18%; p < 0.001), but persisted even at 100 d of age (78% vs 64%; p < 0.02). Region 1 screening resulted in more and earlier cases detected than the other two regions (22 vs 15 per 100,000 births). In 72% of all cases, surgery was performed in response to referrals from either the maternity wards (36%), or the well-baby clinics (36%). However, half of the cases from the well-baby clinics were detected too late, i.e. at > 100 d.

CONCLUSION

Eye screening in the maternity ward is preferable to well-baby clinic screening and to no screening at all, since it leads to early detection. Screening should also be performed routinely at well-baby clinics within the period when successful treatment is possible.

摘要

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