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一种用于阻塞性睡眠呼吸暂停患者启动鼻持续气道正压通气治疗的新颖、简化方法。

A novel, simplified approach to starting nasal CPAP therapy in OSA.

作者信息

Stradling J R, Hardinge M, Smith D M

机构信息

Oxford Centre for Respiratory Medicine, University of Oxford, Oxford Radcliffe Trust, Osler Chest Unit, Churchill Hospital, Oxford OX3 7LJ, UK.

出版信息

Respir Med. 2004 Feb;98(2):155-8. doi: 10.1016/j.rmed.2003.09.010.

Abstract

BACKGROUND

Due to ever increasing referral rates, we have had to move the nasal CPAP induction program for patients with obstructive sleep apnoea (OSA) out of the sleep laboratories and into an outpatient setting. We report the effects this has had on patient outcomes.

METHODS

The last 75 patients with OSA who had an overnight CPAP titration in the sleep laboratory (group 1) were compared with the first 75 coming to an afternoon clinic and set up on CPAP in groups, and who had their CPAP pressure determined from an algorithm (group 2). They were assessed at 1 and 11 months using the Epworth Sleepiness Score, compliance with CPAP (h/night), whether still using CPAP, and the number of clinic appointments required in the first 11 months.

RESULTS

The two groups were similar at baseline. There were no differences in any of the outcome measures. ESS values fell from 14.6 to 5.0 and from 14.0 to 5.1 at 11 months in groups 1 and 2, respectively: compliance, 5.2 versus 5.1 h/night; clinic appointments, 1.75 versus 1.96; discontinuation rates at 1 month, 8% and 7%, and at 11 months, 25% and 21%.

CONCLUSIONS

Using these simple outcome measures, we have shown that using an outpatient-based approach, and CPAP pressure based on an algorithm, have not reduced the efficacy of our CPAP induction program for patients with OSA.

摘要

背景

由于转诊率不断上升,我们不得不将阻塞性睡眠呼吸暂停(OSA)患者的鼻持续气道正压通气(CPAP)诱导计划从睡眠实验室转移到门诊环境中。我们报告了这一举措对患者治疗结果的影响。

方法

将在睡眠实验室进行过夜CPAP滴定的最后75例OSA患者(第1组)与首批75例下午到门诊分组接受CPAP治疗且通过算法确定CPAP压力的患者(第2组)进行比较。在1个月和11个月时,使用Epworth嗜睡量表、CPAP依从性(小时/晚)、是否仍在使用CPAP以及前11个月所需的门诊预约次数对他们进行评估。

结果

两组在基线时相似。任何一项结局指标均无差异。第1组和第2组在11个月时,Epworth嗜睡量表值分别从14.6降至5.0和从14.0降至5.1;依从性分别为5.2小时/晚和5.1小时/晚;门诊预约次数分别为1.75次和1.96次;1个月时停用率分别为8%和7%,11个月时停用率分别为25%和21%。

结论

通过这些简单的结局指标,我们表明采用门诊治疗方法以及基于算法的CPAP压力设置,并未降低我们对OSA患者的CPAP诱导计划的疗效。

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