[异噻唑衍生物的生物活性]
[Biological activity of the isothiazole derivatives].
作者信息
Miedzybrodzki Ryszard
机构信息
Instytut Immunologii i Terapii Doświadczalnej PAN im. Ludwika Hirszfelda we Wrocławiu.
出版信息
Postepy Hig Med Dosw. 2003;57(6):617-30.
PMID:15002160
Abstract
The isothiazole ring was first synthesized in 1956 by Adams and Slack. It was known earlier in condensed structures such as benzisothiazole (saccharin for example). The first found natural origin isothiazole derivative was brassilexin--a phytoalexin from Brassica juncea. In this review diverse biological activity of isothiazole derivatives and their application has been presented.
摘要
异噻唑环于1956年由亚当斯和斯莱克首次合成。它在诸如苯并异噻唑（例如糖精）等稠合结构中早已为人所知。首次发现的天然来源异噻唑衍生物是油菜素——一种来自芥菜的植物抗毒素。在这篇综述中，介绍了异噻唑衍生物的多种生物活性及其应用。
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