Stratelis Georgios, Jakobsson Per, Molstad Siguard, Zetterstrom Olle
Institution of Health and Society, University Hospital, Linkoping, Sweden.
Br J Gen Pract. 2004 Mar;54(500):201-6.
The incidence of chronic obstructive pulmonary disease (COPD) is increasing in developed countries, as is the mortality rate. The main cause of COPD is smoking, and COPD is usually diagnosed at a late stage.
To evaluate a method to detect COPD at an early stage in smokers in a young age group (40-55 years).
Prospective descriptive study.
The city of Motala (45,000 inhabitants) and its surrounding rural areas (43,000 inhabitants) in south-east Sweden. Nineteen thousand, seven hundred and fifty subjects were between 40 and 55 years of age. According to Swedish statistics, approximately 27% of this population are smokers.
Smokers aged between 40 and 55 years were invited to have free spirometry testing in primary healthcare centres. Placards were placed in pharmacies and health centres and advertising was carried out locally twice a year.
A total of 512 smokers responded. The prevalence of COPD was 27% (n = 141). The COPD was classified as mild obstruction in 85% (n = 120), moderate in 13% (n = 18) and severe in 2% (n = 3) according to the European Respiratory Society classification. Knowledge of the disease COPD was acknowledged by 39% of the responders to the questionnaire. Logistic regression analysis showed that age, male sex, number of pack years, dyspnoea and symptoms of chronic bronchitis significantly increased the odds of having COPD. The adjusted odds ratio was significant for having > 30 pack years.
This method of inviting relatively young smokers selected a population of smokers with a high incidence of COPD, and may be one way of identifying smokers with COPD in the early stages.
在发达国家,慢性阻塞性肺疾病(COPD)的发病率和死亡率都在上升。COPD的主要病因是吸烟,且COPD通常在晚期才被诊断出来。
评估一种在年轻年龄组(40 - 55岁)的吸烟者中早期检测COPD的方法。
前瞻性描述性研究。
瑞典东南部的莫塔拉市(45000名居民)及其周边农村地区(43000名居民)。19750名受试者年龄在40至55岁之间。根据瑞典统计数据,该人群中约27%为吸烟者。
邀请年龄在40至55岁之间的吸烟者在初级医疗保健中心进行免费肺活量测定测试。在药店和健康中心张贴海报,并每年在当地进行两次宣传。
共有512名吸烟者做出回应。COPD的患病率为27%(n = 141)。根据欧洲呼吸学会的分类,85%(n = 120)的COPD被分类为轻度阻塞,13%(n = 18)为中度,2%(n = 3)为重度。39%的问卷回复者知晓COPD这种疾病。逻辑回归分析表明,年龄、男性、吸烟包年数、呼吸困难和慢性支气管炎症状显著增加了患COPD的几率。吸烟超过30包年的调整后优势比具有显著性。
这种邀请相对年轻吸烟者的方法筛选出了COPD发病率较高的吸烟者群体,可能是早期识别患有COPD吸烟者的一种方法。