Hensle T W, Bingham J, Lam J, Shabsigh A
Division of Paediatric Urology, Children's Hospital of New York, Columbia University, College of Physicians and Surgeons, NY, USA.
BJU Int. 2004 Mar;93(4):585-7. doi: 10.1111/j.1464-410x.2003.04664.x.
To evaluate the influence of an irrigation protocol in preventing reservoir calculi forming after augmentation cystoplasty and continent urinary diversion.
Between 1985 and 1995, 91 patients had an augmentation cystoplasty and/or continent urinary diversion (group 1; 54 females and 37 males, mean age 11.1 years, range 1-31); these patients were not routinely instructed to use irrigation after surgery. The segments used included ileum (44), colon (36), stomach (eight) and ureter (three). Between 1995 and 2000, 42 patients (group 2) underwent urinary reconstruction (22 females and 20 males, mean age 14.8 years, range 4-27), the segment used being ileum (30), colon (five), ureter (five) and stomach (two) but in contrast to group 1 they then were placed on a standard prophylactic irrigation protocol. The occurrence of stones in the reservoir was then assessed.
Thirty-nine of the 91 patients (42.8%) in group 1 presented with reservoir calculi after reconstruction and 22 had several episodes. The mean time to presentation was 30 months. The incidence of stone formation by underlying diagnosis included: myelomeningocele, 32/48 (66%), exstrophy five/25 (25%), posterior urethral valves two/20 (10%) and rhabdomyosarcoma, none of three. Fifty of the 91 patients had an abdominal stoma, with stone formation in 33 (66%), while 41 used the native urethra, with stone formation in six (15%). Three (7%) of the 42 patients in group 2 developed reservoir calculi after reconstruction, two in patients with myelomeningocele and one in a trauma patient who had residual bone spicules in the bladder; the mean time to presentation was 26.5 months.
These data suggest that the irrigation protocol used in group 2 significantly reduced the number of reservoir calculi after urinary tract reconstruction when bowel was used as part of the reconstruction (43% vs. 7%). The most calculi in both groups were in immobile patients with sensory impairment. Also, patients with an abdominal stoma had a greater risk of reservoir calculi (66%) than those using the native urethra (15%).
评估一种冲洗方案对膀胱扩大成形术和可控性尿流改道术后贮尿囊结石形成的影响。
1985年至1995年间,91例患者接受了膀胱扩大成形术和/或可控性尿流改道(第1组;54例女性和37例男性,平均年龄11.1岁,范围1 - 31岁);这些患者术后未常规接受冲洗指导。所使用的肠段包括回肠(44例)、结肠(36例)、胃(8例)和输尿管(3例)。1995年至2000年间,42例患者(第2组)接受了尿路重建(22例女性和20例男性,平均年龄14.8岁,范围4 - 27岁),所使用的肠段为回肠(30例)、结肠(5例)、输尿管(5例)和胃(2例),但与第1组不同的是,他们随后接受了标准的预防性冲洗方案。然后评估贮尿囊中结石的发生情况。
第1组91例患者中有39例(42.8%)在重建后出现贮尿囊结石,22例有多次发作。出现结石的平均时间为30个月。根据基础诊断的结石形成发生率包括:脊髓脊膜膨出,32/48(66%);膀胱外翻,5/25(25%);后尿道瓣膜,2/20(10%);横纹肌肉瘤,3例中无1例。91例患者中有50例有腹部造口,其中33例(66%)形成结石,而41例使用原尿道,6例(15%)形成结石。第2组42例患者中有3例(7%)在重建后发生贮尿囊结石,2例发生于脊髓脊膜膨出患者,1例发生于膀胱内有残留骨碎片的创伤患者;出现结石的平均时间为26.5个月。
这些数据表明,第2组使用的冲洗方案在尿路重建中使用肠段作为一部分时,显著减少了贮尿囊结石的数量(43%对7%)。两组中大多数结石发生于活动受限且有感觉障碍的患者。此外,有腹部造口的患者发生贮尿囊结石的风险(66%)高于使用原尿道的患者(15%)。