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[佛手和枸杞提取物对小鼠皮肤衰老延缓及毛发生长的影响]

[Effects of the extract from bergamot and boxthorn on the delay of skin aging and hair growth in mice].

作者信息

Shao Lin-xiang

机构信息

College of Life and Environment Science, Zhejiang Normal University, Jinhua 321004, Zhejiang, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2003 Aug;28(8):766-9.

Abstract

OBJECTIVE

To study the effects of the extract from bergamot and boxthorn on the skin and the hair growth in mice.

METHOD

The skin on the back of mice was shaved topically and smeared with bergamot and boxthorn extract for 42 days. Then the activity of superoxide dismutase (SOD) and the content of malondialdehyde (MDA) and collagen in the mice were measured. The growth of hair was also observed.

RESULT

Compared with control group, the extract from bergamot and boxthorn obviously increased the activity of superoxide dismutase (P < 0.05) and the content of collagen (P < 0.001), and decreased the content of malondialdehyde (P < 0.05) in the skin of mice. It also significantly promoted the growth of hair (P < 0.001).

CONCLUSION

The extract from bergamot and boxthorn plays an active role in skin and the promotion of hair growth.

摘要

目的

研究佛手和枸杞提取物对小鼠皮肤及毛发生长的影响。

方法

局部剃除小鼠背部皮肤毛发,涂抹佛手和枸杞提取物,持续42天。然后测定小鼠超氧化物歧化酶(SOD)活性、丙二醛(MDA)含量及胶原蛋白含量,并观察毛发生长情况。

结果

与对照组相比,佛手和枸杞提取物明显提高了小鼠皮肤中超氧化物歧化酶的活性(P < 0.05)和胶原蛋白含量(P < 0.001),降低了丙二醛含量(P < 0.05)。同时,该提取物还显著促进了毛发生长(P < 0.001)。

结论

佛手和枸杞提取物对皮肤及毛发生长具有积极作用。

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