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[脊髓损伤男性患者不育治疗的临床结果]

[Clinical results of infertility treatment to male patients with spinal cord injury].

作者信息

Komiya Atsushi, Sato Kazuhiko, Ishidoh Tetsuo, Tanaka Katsuyuki, Tomoda Takeshi

机构信息

Department of Urology, Social Insurance Sagamino Hospital.

出版信息

Hinyokika Kiyo. 2004 Jan;50(1):21-3.

Abstract

It is difficult for male patients with spinal cord injury (SCI) to have children because of an ejaculation and dysfunction of spermatogenesis. However, owing to progress of assisted reproduction technology in recent years, it has become possible to have children even if the male has SCI, and the rate of success is improving gradually. During the 8 years from 1994 to 2002, infertility treatment was performed on 16 male patients with SCI consulting our hospital for acquistion of a child. We extracted their sperm by electroejaculation (EE) or testicular excision sperm extraction (TESE), and the sperm was artificially inseminated by the techniques such as artificial insemination with husband's semen (AIH), in vitro fertilization (IVF), and intracytoplasmic sperm injection (ICSI). Consequently, it was successful in 14 pregnancies on 10 couples, and resulted in 11 healthy live births on 7 couples. Four cases resulted in abortion. Two spouses are pregnant at present. There were no remarkable differences between the success group and the failure group in the quality of sperm such as concentration and motility. The mean age of the spouses who became pregnant was slightly lower than that of those who did not. Assisted reproduction techniques as EE and ICSI were useful techniques for patients with SCI wishing to have children.

摘要

由于射精及精子发生功能障碍,脊髓损伤(SCI)男性患者生育困难。然而,近年来随着辅助生殖技术的进步,即使男性患有SCI也有可能生育,且成功率在逐渐提高。1994年至2002年的8年间,我们对16名因希望生育而前来我院咨询的SCI男性患者进行了不育治疗。我们通过电射精(EE)或睾丸切除取精术(TESE)提取他们的精子,并采用丈夫精液人工授精(AIH)、体外受精(IVF)和卵胞浆内单精子注射(ICSI)等技术进行人工授精。结果,10对夫妇中有14次妊娠成功,7对夫妇生育了11名健康活产婴儿。4例流产。目前有2名配偶怀孕。成功组和失败组在精子浓度和活力等质量方面无显著差异。成功怀孕的配偶平均年龄略低于未怀孕的配偶。EE和ICSI等辅助生殖技术对希望生育的SCI患者是有用的技术。

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