Matzke Gregory M, Kang Ajaipal S, Dozois Eric J, Sandborn William J
Division of General and Gastroenterologic Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA.
Dis Colon Rectum. 2004 May;47(5):782-6. doi: 10.1007/s10350-003-0105-7. Epub 2004 Mar 25.
A 33-year-old female developed an isolated stricture of the mid portion of her ileal pouch nine years after proctocolectomy and J-ileal pouch-anal anastomosis for ulcerative colitis. Repeated episodes of pouchitis and partial small-bowel obstruction led to pouchoscopy and pouchography, which demonstrated pouch inflammation and a long, tight, midpouch stricture. Her diagnosis was changed to Crohn's disease and she was treated with azathioprine, budesonide, and infliximab. Repeat pouchoscopy demonstrated mucosal healing but a persistent fibrotic stricture. Pouch reconstruction was performed with a midpouch strictureplasty alleviating her obstructive symptoms. One year after surgery, the patient has no clinical evidence of obstruction and repeat pouchography demonstrates a wider pouch lumen across the strictureplasty site. Strictureplasty is an alternative to pouch excision in the management of patients with Crohn's disease who have an isolated pouch stricture.
一名33岁女性在因溃疡性结肠炎接受直肠结肠切除术和J型回肠储袋肛管吻合术9年后,出现了孤立性回肠储袋中段狭窄。反复的储袋炎发作和部分小肠梗阻导致了储袋镜检查和储袋造影,结果显示储袋炎症以及一个长而狭窄的储袋中段狭窄。她的诊断改为克罗恩病,并接受了硫唑嘌呤、布地奈德和英夫利昔单抗治疗。重复储袋镜检查显示黏膜愈合,但纤维化狭窄持续存在。通过储袋中段狭窄成形术进行了储袋重建,缓解了她的梗阻症状。术后一年,患者没有梗阻的临床证据,重复储袋造影显示狭窄成形术部位的储袋腔更宽。在患有孤立性储袋狭窄的克罗恩病患者的管理中,狭窄成形术是储袋切除的一种替代方法。