泰国男性和女性系统性红斑狼疮的临床特征。
Clinical features of systemic lupus erythematosus in Thai males and females.
作者信息
Deesomchok U, Tumrasvin T
机构信息
Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
出版信息
J Med Assoc Thai. 1992 Mar;75(3):133-40.
From 1976 through 1988, 726 patients with systemic lupus erythematosus (SLE) were admitted to the Medical Service of Chulalongkorn Hospital, 666 cases (91.7%) being female and 60 cases (8.3%) male (the female-to-male ratio = 11:1). Clinical comparison of 60 males and 130 females (by randomized selection from the total of 666 females) was made. Onset of disease in males occurred later than in females (29.2 +/- 12.2 years vs 25.8 +/- 10.7 years, p less than 0.01). The majority of clinical manifestations were similar; however, musculoskeletal (63.3 vs 73.3%), cardiac manifestations (13.3 vs 26.1%) and Raynaud's phenomenon (18.3 vs 35.4%) were less common in males than females (p less than 0.01), whereas hematologic manifestations were more common in males than females (p less than 0.01).
1976年至1988年期间，朱拉隆功医院内科收治了726例系统性红斑狼疮（SLE）患者，其中女性666例（91.7%），男性60例（8.3%）（男女比例为11:1）。对60例男性患者和130例女性患者（从666例女性患者中随机选取）进行了临床比较。男性患者的发病时间晚于女性（29.2±12.2岁对25.8±10.7岁，p<0.01）。大多数临床表现相似；然而，男性患者的肌肉骨骼表现（63.3%对73.3%）、心脏表现（13.3%对26.1%）和雷诺现象（18.3%对35.4%）比女性患者少见（p<0.01），而血液学表现男性患者比女性患者更常见（p<0.01）。
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