Walhout Ronald J, Lekkerkerker Jaco C, Oron Gordon H, Bennink Ger B W E, Meijboom Erik J
Children's Heart Center, UMC Utrecht, The Netherlands.
Eur J Cardiothorac Surg. 2004 May;25(5):722-7. doi: 10.1016/j.ejcts.2004.04.008.
Surgery and balloon angioplasty (BA) for coarctation of the aorta have shown comparable short-term results, but long-term follow-up remains unclear. Comparison of surgical repair and balloon coarctation for native coarctation of the localised membranous form is performed retrospectively. To allow a valid comparison between both techniques, identical inclusion criteria were applied.
Results of surgery (group A, 18 patients, age 0.30-14 years, median 0.63 years) and BA (group B, 28 patients, age 0.25-15 years, median 5.8 years) for isolated, native coarctation in children >3 months, performed in a 10-year-period, were compared. Kaplan-Meier analysis was performed in both groups. Mean follow-up ranged from 2.5 to 11 years (mean 7.2+/-2.4 years) in group A and from 1.4 to 10 years (mean 5.4+/-2.8 years) in group B.
Immediate success was obtained in all patients following surgery and 27/28 patients (96%) following BA. No statistical difference between surgery and angioplasty with respect to resultant pressure gradient decreases were found. Mortality was not encountered. Hospital stay varied from 6 to 20 days in group A and was 48 h for all patients in group B. Recoarctation occurred in one patient (5.6%) in group A and in two patients (7%) in group B. Log-rank test reveals no statistical difference in freedom from reintervention probabilities between surgery and angioplasty. Aneurysm formation was not encountered.
Both surgical repair and BA for native coarctation yield low reintervention probabilities in comparable patients. Aneurysm formation was not encountered following different treatment types.
主动脉缩窄的手术治疗和球囊血管成形术(BA)已显示出可比的短期效果,但长期随访结果仍不明确。对局限性膜状型原发性主动脉缩窄的手术修复和球囊缩窄治疗进行回顾性比较。为了对两种技术进行有效比较,采用了相同的纳入标准。
比较了在10年期间对3个月以上儿童的孤立性原发性主动脉缩窄进行手术(A组,18例患者,年龄0.30 - 14岁,中位数0.63岁)和BA(B组,28例患者,年龄0.25 - 15岁,中位数5.8岁)的结果。两组均进行了Kaplan - Meier分析。A组的平均随访时间为2.5至11年(平均7.2±2.4年),B组为1.4至10年(平均5.4±2.8年)。
手术后所有患者以及BA后27/28例患者(96%)即刻获得成功。手术和血管成形术在导致的压力梯度降低方面未发现统计学差异。未发生死亡。A组住院时间为6至20天,B组所有患者住院时间为48小时。A组有1例患者(5.6%)发生再缩窄,B组有2例患者(7%)发生再缩窄。对数秩检验显示手术和血管成形术在再次干预概率的自由度方面无统计学差异。未发现动脉瘤形成。
对于原发性主动脉缩窄,手术修复和BA在可比患者中再次干预概率均较低。不同治疗类型后均未发现动脉瘤形成。