四排多层探测器计算机断层扫描在检测冠状动脉狭窄方面的局限性。
Limitations of four-slice multirow detector computed tomography in the detection of coronary stenosis.
作者信息
Martuscelli Eugenio, Razzini Cinzia, D'Eliseo Alessia, Marchei Massimo, Pisani Eliana, Romeo Francesco
机构信息
Division of Cardiology, Department of Internal Medicine, Tor Vergta University, Rome, Italy.
出版信息
Ital Heart J. 2004 Feb;5(2):127-31.
BACKGROUND
Our aim was to compare 4-slice spiral computed tomography with conventional coronary angiography in the detection of significant (> 50%) coronary stenosis.
METHODS
Sixty-two patients (41 males, 21 females, mean age 60 +/- 8 years) with suspected coronary artery disease were submitted to coronary angiography and then to multislice spiral computed tomography (GE Light Speed 4 slice) performed 12 +/- 5 days later.
RESULTS
We excluded 25% of the patients from analysis because of a heart rate > 70 b/min or because of frequent ectopic beats. We also excluded from analysis 23% of all the angiographic segments judged not evaluable at multislice spiral computed tomography. Within these limits, the sensitivity was 65%, the specificity 98%, the positive predictive value 88%, and the negative predictive value 92%.
CONCLUSIONS
By considering the intrinsic limitations such as its low temporal and spatial resolution, 4-slice spiral computed tomography has a limited applicability and has to be used with caution in the evaluation of native coronary arteries.
背景
我们的目的是比较4层螺旋计算机断层扫描与传统冠状动脉造影在检测显著（>50%）冠状动脉狭窄方面的效果。
方法
62例疑似冠心病患者（41例男性，21例女性，平均年龄60±8岁）接受了冠状动脉造影，然后在12±5天后接受多层螺旋计算机断层扫描（GE Light Speed 4层）。
结果
由于心率>70次/分钟或频发异位搏动，我们将25%的患者排除在分析之外。我们还将多层螺旋计算机断层扫描判定为不可评估的所有血管造影节段中的23%排除在分析之外。在这些限制范围内，敏感性为65%，特异性为98%，阳性预测值为88%，阴性预测值为92%。
结论
考虑到其固有的局限性，如低时间和空间分辨率，4层螺旋计算机断层扫描的适用性有限，在评估自身冠状动脉时必须谨慎使用。
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