Luc Phuong-Van, Tempst Paul
Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Bioinformatics. 2004 Jun 12;20(9):1413-5. doi: 10.1093/bioinformatics/bth114. Epub 2004 Apr 15.
Proteins Interacting in the Nucleus database (PINdb) is a database of protein complexes purified from the nucleus of human and yeast cells. It is compiled from the published literature and existing databases. Currently, PINdb contains mostly protein complexes that may be involved in gene transcription. To facilitate comparative analyses and identification of protein complexes, the compositional information is integrated with standardized gene nomenclature, annotation and protein sequences from public databases. The PINdb web interface provides a number of tools for (1) comparison of protein complexes, (2) search for a protein complex by its published name or by a partial list of its components and (3) browsing specific subsets or a functional classification of the complexes. Availablity: http://pin.mskcc.org
细胞核内相互作用蛋白数据库(PINdb)是一个从人类和酵母细胞核中纯化得到的蛋白质复合物数据库。它是根据已发表的文献和现有数据库汇编而成。目前,PINdb主要包含可能参与基因转录的蛋白质复合物。为便于对蛋白质复合物进行比较分析和鉴定,其组成信息与来自公共数据库的标准化基因命名、注释及蛋白质序列相结合。PINdb网络界面提供了多种工具,用于(1)蛋白质复合物比较,(2)通过已公布的名称或其部分组成列表搜索蛋白质复合物,以及(3)浏览特定子集或复合物的功能分类。获取方式:http://pin.mskcc.org