Barnes J, Sutcliffe A G, Kristoffersen I, Loft A, Wennerholm U, Tarlatzis B C, Kantaris X, Nekkebroeck J, Hagberg B S, Madsen S V, Bonduelle M
Institute for the Study of Children, Families and Social Issues, Birkbeck College, University of London, 7 Bedford Square, London WC1B 3RA, UK.
Hum Reprod. 2004 Jun;19(6):1480-7. doi: 10.1093/humrep/deh239. Epub 2004 Apr 22.
ICSI is used with increasing frequency, but there is less information about the children born following this method of assisted reproduction than other forms of IVF. Some authors have suggested that it may contribute to more family stress than IVF.
ICSI conceived children were compared with IVF conceived children and naturally conceived (NC) controls. They were selected in five European countries: Belgium, Denmark, Greece, Sweden and the UK, and seen for psychological testing and a paediatric examination when they were 5 years old. In all countries, except Greece, mothers and fathers were asked to complete questionnaires about parental well-being, family relationships, parenting and child behaviour.
Very few differences were found between the ICSI and NC group or the ICSI and IVF group. The only significant differences were that mothers in the ICSI conceived group reported fewer hostile or aggressive feelings towards the child and higher levels of commitment to parenting than the mothers of NC children.
The study confirms the results of previous work with IVF families. This should be encouraging for families using these techniques in the future.
卵胞浆内单精子注射(ICSI)的使用频率日益增加,但与其他形式的体外受精(IVF)相比,关于通过这种辅助生殖方法出生的儿童的信息较少。一些作者认为,与IVF相比,它可能会给家庭带来更多压力。
将ICSI受孕儿童与IVF受孕儿童以及自然受孕(NC)对照组进行比较。他们在五个欧洲国家被选中:比利时、丹麦、希腊、瑞典和英国,并在5岁时接受心理测试和儿科检查。在除希腊以外的所有国家,要求母亲和父亲填写关于父母幸福感、家庭关系、育儿和儿童行为的问卷。
在ICSI组与NC组之间或ICSI组与IVF组之间发现的差异很少。唯一显著的差异是,与NC儿童的母亲相比,ICSI受孕组的母亲对孩子表现出较少的敌意或攻击性情绪,并且对育儿的投入程度更高。
该研究证实了先前针对IVF家庭的研究结果。这对未来使用这些技术的家庭应该是一种鼓舞。