Hunter K F, Moore K N, Cody D J, Glazener C M A
Faculty of Nursing/Geriatric Services, University of Alberta/Royal Alexandra Hospital, Edmonton, Alberta, Canada.
Cochrane Database Syst Rev. 2004(2):CD001843. doi: 10.1002/14651858.CD001843.pub2.
Urinary incontinence is common after both radical prostatectomy and transurethral resection. Conservative management includes pelvic floor muscle training, biofeedback, electrical stimulation, compression devices (penile clamps), lifestyle changes, extra-corporeal magnetic innervation or a combination of methods.
To assess the effects of conservative managements for urinary incontinence prostatectomy.
We searched the Cochrane Incontinence Group trials register (searched 2 July 2003), MEDLINE (January 1966 to January 2004), EMBASE (January 1988 to January 2004), CINAHL (January 1982 to January 2004), PsycLIT (January 1984 to January 2004), ERIC (January 1984 to January 2004), the reference lists of relevant articles, handsearched conference proceedings and contacted investigators to locate studies.
Randomised controlled trials evaluating conservative interventions for urinary continence after prostatectomy.
At least two reviewers assessed the methodological quality of trials and abstracted data.
Ten trials met the inclusion criteria, eight trials amongst men after radical prostatectomy, one trial after transurethral resection of prostate and one after either operation. There was considerable variation in the interventions, populations and outcome measures. The trials were of moderate quality and data were not available for many of the pre-stated outcomes. Confidence intervals were wide: it was not possible to reliably identify or rule out a useful effect. There was some support from five trials for pelvic floor muscle training with biofeedback being better than no treatment or sham treatment in the short term for men after radical prostatectomy: relative risk for incontinence with pelvic floor muscle training and biofeedback versus no treatment: 0.74 (95% confidence interval 0.60 to 0.93). Analysis of other conservative interventions such as pelvic floor muscle training alone, transcutaneous electrical nerve stimulation and rectal electrical stimulation, or combinations of these interventions were inconclusive. There were too few data to determine effects on incontinence after transurethral resection of the prostate. The findings should be treated with caution as there were few studies, all of moderate quality. Men in one trial reported a preference for one type of external compression device compared to two others or no treatment. The effect of other conservative interventions such as lifestyle changes remains undetermined as no trials involving these interventions were identified. Men's symptoms tended to improve over time, irrespective of management.
REVIEWERS' CONCLUSIONS: The value of the various approaches to conservative management of postprostatectomy incontinence remains uncertain. There may be some benefit of offering pelvic floor muscle training with biofeedback early in the postoperative period immediately following removal of the catheter as it may promote an earlier return to continence. Long-term incontinence may be managed by external penile clamp, but there are safety problems.
根治性前列腺切除术和经尿道前列腺电切术后尿失禁很常见。保守治疗包括盆底肌训练、生物反馈、电刺激、压迫装置(阴茎夹)、生活方式改变、体外磁神经支配或多种方法联合使用。
评估前列腺切除术后保守治疗对尿失禁的效果。
我们检索了Cochrane尿失禁组试验注册库(2003年7月2日检索)、MEDLINE(1966年1月至2004年1月)、EMBASE(1988年1月至2004年1月)、CINAHL(1982年1月至2004年1月)、PsycLIT(1984年1月至2004年1月)、ERIC(1984年1月至2004年1月),相关文章的参考文献列表,手工检索会议论文集并联系研究者以查找研究。
评估前列腺切除术后尿失禁保守干预措施的随机对照试验。
至少两名评价者评估试验的方法学质量并提取数据。
10项试验符合纳入标准,8项试验针对根治性前列腺切除术后的男性,1项试验针对经尿道前列腺电切术后的男性,1项试验针对两种手术之一后的男性。干预措施、研究对象和结局指标存在很大差异。试验质量中等,许多预先设定的结局指标没有可用数据。置信区间很宽:无法可靠地确定或排除有益效果。5项试验提供了一些支持,表明对于根治性前列腺切除术后的男性,盆底肌训练联合生物反馈在短期内比不治疗或假治疗更有效:盆底肌训练联合生物反馈与不治疗相比,尿失禁的相对风险为0.74(95%置信区间0.60至0.93)。对其他保守干预措施(如单独的盆底肌训练、经皮电神经刺激和直肠电刺激,或这些干预措施的联合使用)的分析尚无定论。经尿道前列腺电切术后关于对尿失禁影响的数据太少,无法确定。由于研究很少且质量均为中等,这些结果应谨慎对待。一项试验中的男性报告称,与另外两种或不治疗相比,他们更喜欢一种外部压迫装置。由于未发现涉及生活方式改变等其他保守干预措施的试验,其效果仍未确定。无论采用何种治疗方法男性的症状往往会随时间改善。
前列腺切除术后尿失禁各种保守治疗方法的价值仍不确定。术后拔除导尿管后早期提供盆底肌训练联合生物反馈可能有益,因为它可能促进更早恢复控尿。长期尿失禁可通过外部阴茎夹治疗,但存在安全问题。