伴有低钠血症和低抗利尿激素水平的未成熟卵巢畸胎瘤。
Immature ovarian teratoma with hyponatremia and low antidiuretic hormone level.
作者信息
Roman Horace, Verspyck Eric, Sentilhes Loïc, Barau Georges
机构信息
Department of Gynecology and Obstetrics, Groupe Hospitalier Sud Réunion, St. Pierre, Reunion Island, France.
出版信息
Obstet Gynecol. 2004 May;103(5 Pt 2):1108-10. doi: 10.1097/01.AOG.0000123244.53438.58.
BACKGROUND
Inappropriate antidiuretic hormone secretion syndrome is rare in patients with gynecologic tumors.
CASE
A 22-year-old woman presented with inappropriate antidiuretic hormone secretion symptoms during the 2 months preceding the diagnosis of an immature ovarian teratoma. Vasopressin levels in serum and in the urine were very low. Restriction of water intake and surgical removal of the teratoma resulted in the definitive correction of the hyponatremia. This observation suggests that immature teratoma cells can produce a vasopressin-like factor, and the syndrome may be a sign of an ovarian malignancy.
CONCLUSION
Pelvic organs should be examined when the more common causes of inappropriate antidiuretic hormone secretion syndrome have been ruled out.
背景
抗利尿激素分泌不当综合征在妇科肿瘤患者中较为罕见。
病例
一名22岁女性在未成熟卵巢畸胎瘤诊断前2个月出现抗利尿激素分泌不当症状。血清和尿液中的血管加压素水平极低。限制水摄入并手术切除畸胎瘤后，低钠血症得到了彻底纠正。这一观察结果表明，未成熟畸胎瘤细胞可产生血管加压素样因子，该综合征可能是卵巢恶性肿瘤的一个征象。
结论
当排除了抗利尿激素分泌不当综合征更常见的病因后，应检查盆腔器官。
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