Pavone Vito, Johnson Timothy, Saulog Penny S, Sculco Thomas P, Bottner Friedrich
Hospital for Special Surgery, New York, NY 10021, USA.
Clin Orthop Relat Res. 2004 Apr(421):155-61. doi: 10.1097/01.blo.0000126309.72205.f7.
A retrospective review was done on 501 patients who had bilateral sequential one-stage total knee replacements from September 1995 to April 2000 to evaluate perioperative (inhospital) morbidity. One thousand two knee replacements were done with the patients receiving regional anesthesia, on 286 women and 215 men with an average age of 66 years. The average transfusion requirement was 2.8 units of blood per patient. There were no deaths, myocardial infarctions, or cerebrovascular accidents. The mean length of hospital stay was 7.2 days. One hundred forty-four perioperative complications were observed in 109 patients (21.8%). These complications included 27 arrhythmias (5%), one congestive heart failure (0.2%), 65 lower extremity deep venous thromboses (13%), 14 fat emboli (3%), and two pulmonary emboli (0.4%). Other major complications were pneumonia (1%), acute renal failure (0.4%), ileus (2%), and mental status changes (2%). Wound complications included two deep infections (0.4%), three hematomas (0.6%), and five delayed wound healings (0.9%). According to the current study the perioperative morbidity and mortality is acceptable if the procedure is used for selected patients. Patients with significant comorbidities should have a staged bilateral total knee replacement.
对1995年9月至2000年4月期间接受双侧序贯一期全膝关节置换术的501例患者进行了回顾性研究,以评估围手术期(住院期间)发病率。共进行了1002例膝关节置换术,患者接受区域麻醉,其中286例女性和215例男性,平均年龄66岁。每位患者的平均输血量为2.8个单位。无死亡、心肌梗死或脑血管意外发生。平均住院时间为7.2天。109例患者(21.8%)出现144例围手术期并发症。这些并发症包括27例心律失常(5%)、1例充血性心力衰竭(0.2%)、65例下肢深静脉血栓形成(13%)、14例脂肪栓塞(3%)和2例肺栓塞(0.4%)。其他主要并发症包括肺炎(1%)、急性肾衰竭(0.4%)、肠梗阻(2%)和精神状态改变(2%)。伤口并发症包括2例深部感染(0.4%)、3例血肿(0.6%)和5例伤口延迟愈合(0.9%)。根据当前研究,如果该手术用于特定患者,围手术期发病率和死亡率是可以接受的。患有严重合并症的患者应分期进行双侧全膝关节置换术。