药物性心脏毒性：强调心电图在临床研究和药物研发中的作用。
Drug-induced cardiac toxicity: emphasizing the role of electrocardiography in clinical research and drug development.
作者信息
Gussak Ihor, Litwin Jeffrey, Kleiman Robert, Grisanti Scott, Morganroth Joel
出版信息
J Electrocardiol. 2004 Jan;37(1):19-24. doi: 10.1016/j.jelectrocard.2003.11.003.
Abstract
This review describes the role of electrocardiography in clinical research and drug development, and addresses its utility in defining cardiac toxicity from noncardiac investigational drugs. Principles for designing electrocardiographic monitoring for cardiac safety in clinical trials are also reviewed.
摘要
本综述描述了心电图在临床研究和药物开发中的作用，并探讨了其在确定非心脏研究药物所致心脏毒性方面的效用。还综述了在临床试验中设计用于心脏安全性的心电图监测的原则。
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