镰状细胞脑血管疾病：磁共振成像和磁共振血管造影的常见及不常见表现

Sickle cell cerebrovascular disease: usual and unusual findings on MR imaging and MR angiography.

作者信息

Moritani Toshio, Numaguchi Yuji, Lemer Norma B, Rozans Martha K, Robinson Avin E, Hiwatashi Akio, Westesson Per-Lennart

机构信息

Department of Radiology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 648, Rochester, NY 14642, USA.

出版信息

Clin Imaging. 2004 May-Jun;28(3):173-86. doi: 10.1016/S0899-7071(03)00121-9.

DOI:10.1016/S0899-7071(03)00121-9

PMID:15158221

Abstract

This paper demonstrates usual and unusual findings on MR imaging (MRI) including fluid-attenuated inversion recovery (FLAIR), diffusion- and perfusion-weighted image and MR angiography (MRA) in 30 patients with sickle cell cerebrovascular disease. This paper also illustrates the underlying pathophysiology of sickle cell cerebrovascular disease by using the cases with usual and unusual MR findings, including long-time follow-up cases during transfusion therapy. MRI and MRA are useful in defining the basis for stroke and assessing the effects of chronic transfusion therapy.

摘要

本文展示了30例镰状细胞脑血管疾病患者在磁共振成像（MRI）上的常见和不常见表现，包括液体衰减反转恢复序列（FLAIR）、扩散加权成像、灌注加权成像及磁共振血管造影（MRA）。本文还通过具有常见和不常见磁共振表现的病例，包括输血治疗期间的长期随访病例，阐述了镰状细胞脑血管疾病的潜在病理生理学。MRI和MRA有助于明确中风的病因并评估慢性输血治疗的效果。