Ozkan Neslihan, Altan Lale, Bingöl Umit, Akln Selçuk, Yurtkuran Merih
Atatürk Rehabilitation Center, Rheumatic Disease and Hydrotherapy Section, Uludağ University Medical Faculty, Bursa, Turkey.
J Clin Laser Med Surg. 2004 Apr;22(2):105-10. doi: 10.1089/104454704774076154.
To investigate the effect of laser photostimulation in rehabilitation of human digital flexor tendons with a placebo-controlled double-blind prospective study model.
Low-energy laser therapy has been applied in several rheumatoid and soft tissue disorders with a varying rate of success and it has also been shown to have a positive effect on tendon healing in animal experiments, but no clinical study on laser photostimulation in the treatment of human tendons has been reported to date.
This study was performed in a total of 25 patients with 41 digital flexor tendon injuries in five anatomical zones. In Group I (21 digits in 13 patients), whirlpool and infrared GaAs diode laser with a frequency of 100 Hz. was applied between the 8th and 21st days postoperatively and all patients were given the Washington rehabilitation program until the end of the 12th week. In Group II (20 digits in 12 patients), the same treatment protocol was given but the laser instrument was switched off during applications.
The results of the study showed a significant improvement in the laser-treated group only for the parameter of edema reduction (p < 0.01) but the difference between the two groups was non-significant for pain reduction, hand grip strength, and functional evaluation performed according to Strickland and Buck-Gramcko systems using total active motion and fingertip-to distal palmar crease distance parameters (p > 0.05).
Significant improvement obtained in edema reduction both immediately and 12 weeks after supplementary GaAs laser application in our study has been interpreted as an important contribution to the rehabilitation of human flexor tendon injuries because edema is known to have a detrimental effect on functional recovery during both early and late stages of tendon healing. However, our study has failed to show a significant positive effect of supplementary GaAs laser application on the other functional recovery parameters of human flexor tendon injury rehabilitation and we suggest further clinical study in this topic be done using different laser types and dosages in order to delineate the role of this promising treatment modality.
采用安慰剂对照双盲前瞻性研究模型,探讨激光光刺激对人类指屈肌腱康复的影响。
低能量激光疗法已应用于多种类风湿性疾病和软组织疾病,成功率各异,且在动物实验中也显示对肌腱愈合有积极作用,但迄今为止,尚无关于激光光刺激治疗人类肌腱的临床研究报道。
本研究共纳入25例患者,其41条指屈肌腱在五个解剖区域受伤。第一组(13例患者的21根手指),术后第8天至第21天采用漩涡浴和频率为100Hz的红外砷化镓二极管激光治疗,所有患者均接受华盛顿康复计划直至第12周结束。第二组(12例患者的20根手指),给予相同的治疗方案,但在治疗过程中关闭激光仪器。
研究结果显示,仅激光治疗组在减轻水肿参数方面有显著改善(p < 0.01),但两组在减轻疼痛、握力以及根据斯特里克兰德和巴克 - 格拉姆科系统使用总主动活动和指尖至远端掌横纹距离参数进行的功能评估方面差异无统计学意义(p > 0.05)。
在我们的研究中,补充应用砷化镓激光后立即及12周后水肿减轻均有显著改善,这被认为对人类屈肌腱损伤的康复有重要贡献,因为已知水肿在肌腱愈合的早期和晚期对功能恢复均有不利影响。然而,我们的研究未能显示补充应用砷化镓激光对人类屈肌腱损伤康复的其他功能恢复参数有显著的积极作用,我们建议针对该主题进一步开展临床研究,使用不同类型和剂量的激光,以明确这种有前景的治疗方式的作用。